Spontaneous perforation of the bile duct is a rare but well documented condition of infants. Six infants are described, five presenting within 2 months of birth without apparent antecedent factors and one associated with an 'acquired' type I biliary atresia at 8 months. All infants underwent definitive surgery, which included decompression of the biliary tree with cholecystenterostomy or T tube...

Manuscript received and accepted: 2 August and 15 September 2008 Biliary atresia is a rare disease characterized by a biliary obstruction of unknown origin that presents in the neonatal period. We present the magnetic resonance cholangiography (MRC) from a 25 years old women who was treated in the neonatal period with Kasai operation. The MRC reveals a choledochal cyst and shows multiple saccul...

Long term survival for decades after portoenterostomy (Kasai procedure) for biliary atresia is rare and the association of portoenterostomy with liver cirrhosis is well known. Not much attention was given in the evaluation of the imaging features of cirrhosis caused by portoenterostomy as received by other known usual causes of cirrhosis. We presented a case of a Nigerian with confirmed biliary...

CHIBA, S., FUJIWARA, T., SHIONO, H. and NAKAO, T. Frequency of Australia Antigen Detected by Radioimmunoassay in Hepatitis in Children . Tohoku J. exp. Med., 1973, 109 (3), 307-308 Ninety-eight serum specimens obtained from 53 cases of hepatitis in children and 11 specimens from 10 cases of biliary atresia were tested for Australia (Au) antigen by radioimmunoassay (RIA) . Au antigen was detecte...

Recognition of neonatal liver disease has been heavily dependent on the occurrence of jaundice. In most instances the jaundice is related to specific disturbances in bilirubin transport and other tests of liver function are normal. In contrast, hepatitis and other liver diseases not specifically affecting bilirubin transport often go undetected unless jaundice occurs. The development of practic...

To provide an objective rapid means of excluding extrahepatic biliary atresia (atresia), a hepatic index was devised from the ratio of the net hepatic to cardiac distribution of 99mTc diisopropyl iminodiacetic acid or methylbrom iminodiacetic acid between 2.5 and 10 minutes after injection. The hepatic index was compared with subjective assessment of abdominal scintigraphy performed repeatedly ...

Microcirculation lesion is a common symptom of chronic liver diseases in the form of vasculature deformation and circulation alteration. In acute to chronic liver diseases such as biliary atresia, microcirculation lesion can have an early onset. Detection of microcirculation lesion is meaningful for studying the progression of liver disease. We have combined wide-field fluorescence microscopy a...