Medicinal plants have been used since remote times in folk medicine and they are now a part of the people inheritage. Through North African countries, todays folk medicine has been boosted as a consequence of hard economic conditions. Because of its geographical situation, climate and soil composition, Tlemcen's region offers a wide variety of plants and flowers. The frequent usage of medicinal...

The kidneys are important organs which have many functions in the body, including the production of hormones, absorbtion of minerals and the filtration of blood, producing urine. Their failure can be fatal, therefore, to focus the study of such herbs which may be useful in treating renal disease is the need of hour. In Pakistan, Cucumis melo and Berberis vulgaris has been commonly used for rena...

OBJECTIVE It has been shown that berberine, a major component of Berberis vulgaris extract, modulates the activity of several neurotransmitter systems including dopamine (Da) and N-methyl-D-aspartate (NMDA) contributing to rewarding and reinforcing effects of morphine. Drug craving and relapsing even after a long time of abstinence therapy are the most important problems of addiction. In the pr...

Many herbaceous plants contain compounds that have biological effects in addition to their medicinal properties. They have compounds with numerous properties, including hypo lipidemic, hypoglycemic, antioxidant, and hepato protective ones, which have been analyzed at different levels. One of these plants, with the scientific name of Berberis vulgaris, is barberry. The most important compounds i...

Background and objectives: Berberis vulgaris L (Berberidaceae) is a medicinal plant that is distributed in different parts of Iran; it is grown as a wild or cultivated plant. It has different pharmacological activities such as antioxidant, anti-inflammatory, anti-arrhythmic, sedative and anti-malaria effects. In this study, the anti-seizure activity of different fracti...

Objective: Antiepileptic drugs (AEDs) that are usually used for treatment of epilepsy have substantial side effects and about 30% of patients continue to have seizures with current AEDs therapy. Some herbs which traditionally used in the management of seizures of many rural areas of the developing countries have shown anticonvulsant activity in modern pharmacological bioassays. The aim of the p...

Continuous efforts are being made to develop new drugs or dietary supplements from natural products. These efforts are important in improving the outcomes of many intractable diseases. In an article published in this issue of the International Neurourology Journal, the antiapoptotic effect of berberine against ischemic brain injury in gerbils has been reported [1]. The authors suggest that this...

In the present study, the application of a BP neural network for prediction of the moisture content of barberry fruit (berberis vulgaris) during drying was investigated. The important parameters namely, pretreatment (heat shocking, olive oil + K2CO3 and NAT), air drying temperature (60, 70 and 80oC), air drying velocity (0.3, 0.5 and 1 m/s) and time (s) were considered as the input parameters a...

Metformin has been used as a glucose lowering drug for several centuries and is now a first-line drug for type 2 diabetes mellitus (T2DM). Since the discovery that it activates AMP-activated protein kinase (AMPK) and reduces risk of cancer, metformin has drawn great attentions. Another drug, berberine, extracted from berberis vulgaris L. (root), was an ancient herbal medicine in treating diarrh...