Analysis of meiotic recombination by functional genomic approaches reveals prominent spatial and functional interactions among diverse organizational determinants. Recombination occurs between chromatin loop sequences; however, these sequences are spatially tethered to underlying chromosome axes via their recombinosomes. Meiotic chromosomal protein, Red1, localizes to chromosome axes; however, ...

QTL mapping: The AW33 QTL was shown to be linked to microsatellite MCW0170, and the ST53 QTL was tightly linked to MCW0114, both markers located on GGA4. Our results demonstrate that these markers and therefore the associated QTLs, map within the GGA4q21–q22 and GGA4q11–12 regions, respectively. These results provide multiple entry points into the physical map and sequence of the chicken genome...

abstract to identify the species, understanding the characteristics of the species, explore the possibility of speciation, mutations in the study population, and many other purposes. in this method for studying colchesin bath, karyotype use for immature worms. after reviewing the slide karyotype of polychaeta (nereis sp.) and observation and analysis of  50  plaque metaphase plate chromosome nu...

background: lymphocytes of fanconi anemia (fa) show an increased sensitivity to the alkylating agents such as mitomycin c (mmc), but their responses to gamma-irradiation is controversial. the extent of dna damage in leukocytes of fa patients following irradiation and mmc treatment was studied at cellular and single chromosome level. methods: dna damage induced by gamma-rays and mmc was measured...

Early childhood caries affects 28% of children aged 2-6 in the US and is not decreasing. There is a well-recognized need to identify susceptible children at birth. Caries-free adults neutralize bacterial acids in dental biofilms better than adults with severe caries. Saliva contains acidic and basic proline-rich proteins (PRPs) which attach to oral streptococci. The PRPs are encoded within a sm...

A new species Ixeridium calcicola (Compositae) endemic to middle altitude (ca 1,000-2,000 m asl) limestone mountains of eastcentral Taiwan is described based on morphological and chromosome cytological observations and molecular phylogenetic analyses. Ixeridium calcicola resembles Ixeridium transnokoense, endemic to upper montane and alpine ranges (2,600-3,500 m asl) of Taiwan, in the dwarf hab...

background: while multiple factors can contribute to male infertility, genetic factors, such as chromosomal disorders or y-chromosome microdeletion, are responsible for about 10% of male infertility. considering the role of y-chromosome microdeletions in men with oligozoospermia who volunteer for in vitro fertilization (ivf), the prevalence of such microdeletions in each particular community ne...

 Abstract Background: To produce a reliable probe suitable for aneuploidy detection of chromosome 13 on uncultured lymphocytes and amniocytes by fluorescence in situ hybridization (FISH), we used a contig of three overlapping cosmids mapped to 13q12.3. Methods: The cosmid DNA carrying the expected sequences of human chromosome 13 was isolated from host cells and labelled with biotin-11-dUTP. Th...

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Observation of the internal ultrastructure of human chromosomes by transmission electron microscopy (TEM) has been hampered due to the difficulties in detaching metaphase chromosome spreads from the glass slide for further processing. We used a method in which the metaphase chromosome spreads were prepared on a flexible thermoplastic membrane, ACLAR film. To assess chromosome identity, a diamid...