نتایج جستجو برای: atria
تعداد نتایج: 3555 فیلتر نتایج به سال:
Atrial distension, which stimulates atrial natriuretic peptide secretion by atrial myocytes, also stretches nonmuscle cells. In a noncontracting in vitro preparation of combined right and left atria we demonstrated by electron microscopy that, at 37°C, transition from zero pressure to a physiological distending pressure of 5.1 mm Hg rapidly rendered atrial endocardial endothelium permeable to t...
We used standard nicroketrode to record action potentials of human right trial fibers obtained during cardiac surgery, and correlated these potential with dinical and preoperative ECG data. Human atrial fibers were classified as follows: Group A (ten patients) had a maximum diastolic potential (MDP) of -71.4 ± 5.1 mV (mea ± SD), and actin potentials that were primarily fast pe These atria were ...
Background: The role of citalopram (a tricyclic antidepressant of SSRI group) on ouabain-induced arrhythmia in guinea pig was well established. Materials and methods: Thirty-two guinea pigs were randomly assigned in any of the four groups citalopram, ouabain, citalopram+ouabain, and control. The Na, K, and Ca concentrations were measured using atomic absorption technique. Results: Citalopram ...
BACKGROUND Accurate risk stratification is considered the first and most important step in the management of patients with non-valvular atrial fibrillation (NVAF). We compared the performance of the widely used CHA2DS2-VASc and the recently developed R2CHADS2 and ATRIA scores, for predicting thromboembolic (TE) event in either non-anticoagulated or anticoagulated patients with NVAF. METHODS T...
OBJECTIVES We investigated expression of brain natriuretic peptide (BNP) as well as atrial natriuretic peptide (ANP) and their genes in human right atria. Their relations with atrial pressure were also examined. BACKGROUND The BNP plays a roll in electrolyte-fluid homeostasis such as ANP. The tissue level is reported to be elevated in the failing ventricles. However, expression and transmural...
BACKGROUND Nitric oxide (NO) synthesized within sinoatrial cells recently has been shown to participate in the autonomic control of heart rate. We hypothesized that NO in the neuronal cells in the heart was increased and parasympathetically regulated heart rate after myocardial infarction (MI). METHODS AND RESULTS We examined heart rate dynamics and neuronal NO synthase (nNOS) expression and ...
Although t-tubules have traditionally been thought to be absent in atrial cardiomyocytes, recent studies have suggested that t-tubules exist in the atria of large mammals. However, it is unclear whether regional differences in t-tubule organization exist that define cardiomyocyte function across the atria. We sought to investigate regional t-tubule density in pig and rat atria and the consequen...
Stored cardiac pro-atrial natriuretic peptide (pro-ANP) is converted to ANP and released upon stretch from the atria into the circulation. Corin is a serin protease with pro-ANP-converting properties and may be the rate-limiting enzyme in ANP release. This study was aimed to clone and sequence corin in the rat and to analyze corin mRNA expression in heart failure when ANP release upon stretch i...
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