نتایج جستجو برای: angiotensins
تعداد نتایج: 23319 فیلتر نتایج به سال:
OBJECTIVES The purpose of this study was to investigate the effect of angiotensin II (AII) and angiotensin IV (AIV, 3-8 fragment of AII) on the cell proliferation in the anterior pituitary of rat in vivo. MATERIALS AND METHODS The female adult Wistar rats, ovariectomized 10 days before experiment were injected intraperitoneally with saline, AII, AIV and AII or AIV together with losartan--the ...
BACKGROUND We examined the effect of chronic administration of angiotensin IV (AngIV) on the vascular alterations induced by type 1 diabetes in mice. METHODS Diabetes was induced in adult Swiss mice with a single injection of streptozotocin (STZ). Mice were treated subcutaneously with AngIV (1.4 mg/kg/day) either immediately following diabetes induction (preventive treatment), or treated with...
Microvillar membranes derived from the brush border of the renal proximal tubule are very rich in peptidases. Pig kidney microvilli contain endopeptidase-24.11 associated with a battery of exopeptidases. The manner by which some neuropeptides are degraded by the combined attack of the peptidases of this membrane has been investigated. The contribution of individual peptidases was assessed by in...
OBJECTIVE The aim of the present study was to elucidate the presence in rat cardiac fibroblastic cells of arginine-aminopeptidase and its involvement in the hydrolysis of angiotensin peptides. METHODS Peptidase activity was measured as hydrolysis of the synthetic substrates, aryl-p-nitroanilides. Immunoblottings were performed with antibodies to aminopeptidase B and Glyceraldehyde-3-phosphate...
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