Objective: This study aimed to verify the effect of preemptive administration dexamethasone 8 mg co-administered with paracetamol 1 g compared nimesulide 100 in surgeries for extracting third molars. Methods: A prospective, randomized, triple-blind clinical trial was conducted, allocating patients into two groups by split-mouth method: Group received and paracetamol, 2 nimesulide. Each patient ...

OBJECTIVES Effective postoperative pain management is crucial in the care of surgical patients. Opioids, which are commonly used in managing postoperative pain, have a potential for tolerance and addiction, along with sedating side effects. Gabapentin's use as a multimodal analgesic regimen to treat neuropathic pain has been documented as having favorable side effects. This meta-analysis examin...

BACKGROUND Several additives have been suggested to enhance analgesic effect of local anesthetic agents to decrease the adverse effects of them and increase the degree of satisfaction. We designed this randomized double-blind controlled study to evaluate the analgesic efficacy of the neostigmine added to bupivacaine using spinal anesthesia in patients undergoing lower limb orthopedic surgery. ...

results there were no significant differences between the two groups with respect to age, gender, nausea and vomiting, sleep quality, blood pressure, and heart rate. no significant differences were observed between the two groups in pain scores (p = 0.39) and analgesic consumption (p = 0.78). conclusions the results suggest that a single dose of preoperative oral amantadine did not reduce acute...

BACKGROUND The aim of this study was to compare the pain-relieving effect and the subjective well-being between auricular electro-acupuncture (EA) analgesia, auricular acupuncture (A) and conventional analgesia with remifentanil (CO). METHODS A total of 94 women undergoing IVF were randomized to auricular acupuncture with (EA, n = 32) or without (A, n = 32) continuous 1 Hz auricular stimulati...

BACKGROUND Perioperative pain treatment often consist of combinations of non-opioid and opioid analgesics, 'multimodal analgesia', in which gabapentin is currently used. The aim was to document beneficial and harmful effects of perioperative gabapentin treatment. METHODS Randomized clinical trials comparing gabapentin vs. placebo or active placebo in adult surgical patients receiving gabapent...

BACKGROUND AND OBJECTIVES Intraoperative use of opioids may be associated with postoperative hyperalgesia and increased analgesic consumption. Side effects due to perioperative use of opioids, such as postoperative nausea and vomiting may delay discharge. We hypothesized that total intravenous anesthesia consisting of lidocaine and dexmedetomidine as an opioid substitute may be an alternative t...

AIMS To evaluate the impact of temporomandibular disorder (TMD) pain by age and gender in adolescents, with assessments of this impact specifically on school absence, medication consumption, perceived need for treatment, jaw function limitation, depressive symptoms scores and somatic complaints, and graded chronic pain scale. METHODS In a population-based sample, a mailed questionnaire was se...

Introduction: This study has aimed to research the analgesic effects of lidocaine and dexamethasone infiltration in the merocel pack which is being used as nose pack for patients who had septoplasty operation. Materials and Methods: Sixty patients are included in randomized double blind study. The patients are divided into 3 groups as lidocaine (group L), lidocaine + dexamethasone (group LD) an...