Monitoring of energy distribution of the three macronutrients of diet could be beneficial in order to improve the physiological status of elderly people. The objective of this study is to analyse total daily energy intake as well as the caloric contribution of the macronutrients and alcohol, which make up basic diet of five nursing homes in León (Spain). Dietary consumption was evaluated in a g...

Deficient dietary folate intake may predispose individuals to cancer as a consequence of disruption of DNA synthesis, repair, and methylation (1,2); diets deficient in methyl groups may result in the activation of oncogenes and inactivation of tumor suppressor genes (3). Relatively low intake of methionine and relatively high intake of alcohol may increase folate requirements, the former by red...

BACKGROUND Daily alcohol intake in quantities as small as half a drink/day significantly increases the risk of breast cancer recurrence for postmenopausal survivors. Interventions designed to modify alcohol use among survivors have not been studied; however, lifestyle interventions that target change in dietary intake may affect alcohol intake. OBJECTIVE To evaluate change in alcohol use duri...

Excessive alcohol consumption is the third leading contributor to preventable death worldwide, contributing to 2.5 million deaths per year (1–3). Casual drinking is an aspect of the typical diet in many parts of the world. Yet, excessive alcohol consumption has a devastating effect on public health. Excessive drinking, which is correlated with alcoholism (4), is a serious concern and levies a p...

Chronic alcohol intake leads to insulin resistance and alcoholic cardiomyopathy, which appears to be a result of the complex interaction between genes and environment. This study was designed to examine the impact of aldehyde dehydrogenase-2 (ALDH2) transgenic overexpression on alcohol-induced insulin resistance and myocardial injury. ALDH2 transgenic mice were produced using chicken beta-actin...

The effects of long-term alcohol intake and pancreatic secretory stimulation on pancreatic necrosis were studied in rats with acute pancreatitis induced by an intraductal injection of sodium taurocholate. Neither alcohol nor pancreozymin alone influenced the extent of pancreatic tissue damage in this experimental model. However, when animals were exposed to both alcohol and pancreozymin, the ti...

OBJECTIVES To assess the effect of periodic and moderate alcohol intake on gallbladder motility. METHODS The ultrasonographic ellipsoid method was used in 21 healthy male subjects: 12 non-alcohol and 9 alcohol drinkers. The stimulus for gallbladder contraction was 165 ml of half cream milk. Gallbladder dynamics were studied for 20 minutes following the ingestion of the milk. The mean percenta...

BACKGROUND Alcohol intake has been associated with reduced incidence of common cold symptoms in 2 European studies. However, no study has addressed the association between the frequency of alcohol intake and the incidence of common cold. This study aimed to investigate the association between the amount and frequency of alcohol drinking and the retrospective prevalence of common cold in Japanes...

OBJECTIVE Recent studies suggest a lower risk for overweight/obesity in moderate alcohol drinkers. However, the validity of this relationship and its impact on the putative benefits of alcohol consumption on cardiovascular disease (CVD) risk has not been well evaluated. RESEARCH DESIGN AND METHODS We assessed the impact of BMI on the relationship between alcohol consumption and CVD risk facto...

Dopamine (DA) signals are transmitted via specific receptors including the D2 receptors (D2R). Previous studies have shown that D2R upregulation in the nucleus accumbens (NAc) attenuated alcohol consumption. We hypothesized that upregulation of D2R in the NAc would significantly influence alcohol drinking. We tested this hypothesis by determining the effect that D2R upregulation has on alcohol ...