HYDROXYUREA is a cytotoxic drug which has recently been investigated as a therapeutic agent in a number of malignant conditions, e.g. cancer of the head and neck (Beckloff, 1967), and leukaemia especially chronic myeloid leukaemia (Malpas, 1967; Weil and Tanzer, 1967). It is not a new compound but has only recently been screened for activity against cancer. It is believed that the activity of h...