نتایج جستجو برای: wnt inhibitory factor 1

تعداد نتایج: 3433943  

Journal: :Molecular cancer therapeutics 2010
Elyssa M Rubin Yi Guo Khoa Tu Jun Xie Xiaolin Zi Bang H Hoang

It has been reported that the progression of osteosarcoma was closely associated with the aberrant activation of canonical Wnt signaling. Wnt inhibitory factor-1 (WIF-1) is a secreted Wnt inhibitor whose role in human osteosarcoma remains unknown. In this study, WIF-1 expression in NHOst and osteosarcoma cell lines was determined by real-time reverse transcription-PCR, methylation-specific PCR,...

Journal: :Journal of cell science 2003
Yoshiaki Kawano Robert Kypta

The extracellular antagonists of the Wnt signalling pathway can be divided into two broad classes. Both classes of molecule prevent ligand-receptor interactions, but by different mechanisms: members of the first class, which include the sFRP (secreted Frizzled-related protein) family, WIF (Wnt inhibitory factor)-1 and Cerberus, primarily bind to Wnt proteins; the second class comprises certain ...

Journal: :international journal of fertility and sterility 0
mohammad zandi syed mohamad shah musharifa muzaffar manoj kumar singh prabhat palta suresh kumar singla

background: this research studies the effects of activation and inhibition of wnt3a signaling pathway in buffalo (bubalus bubalis) embryonic stem (es) cell-like cells. materials and methods: to carry on this experimental study, the effects of activation and inhibition of wnt3a signaling in buffalo es cell-like cells were examined using bio (0.5 mm) combined with wnt3a (200 ng/ml), as an activat...

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