نتایج جستجو برای: white matter lesions

تعداد نتایج: 526058  

Journal: :Cerebrovascular diseases 2002
Frederik Barkhof Philip Scheltens

Magnetic resonance imaging (MRI) is very sensitive for the detection of white matter lesions (WML), which occur even in normal ageing. Intrinsic WML should be separated from physiological changes in the ageing brain, such as periventricular caps and bands, and from dilated Virchow-Robin spaces. Genuine WML are best seen with T2-weighted sequences such as long TR dual-echo spin-echo or FLAIR (fl...

Journal: :AJNR. American journal of neuroradiology 2017
X Li J Gao M Wang J Zheng Y Li E S Hui M Wan J Yang

BACKGROUND AND PURPOSE Punctate white matter lesions are common in preterm neonates. Neurodevelopmental outcomes of the neonates are related to the degree of extension. This study aimed to characterize the extent of microstructural variations for different punctate white matter lesion grades. MATERIALS AND METHODS Preterm neonates with punctate white matter lesions were divided into 3 grades ...

Journal: :Hypertension 2004
Ewoud J van Dijk Monique M B Breteler Reinhold Schmidt Klaus Berger Lars-Göran Nilsson Matthijs Oudkerk Andrzej Pajak Susana Sans Maria de Ridder Carole Dufouil Rebecca Fuhrer Simona Giampaoli Lenore J Launer Albert Hofman

Cerebral white matter lesions are frequently observed on magnetic resonance imaging (MRI) scans in elderly people and are associated with stroke and dementia. Elevated blood pressure is presumed one of the main risk factors, although data are almost exclusively derived from cross-sectional studies. We assessed in 10 European cohorts the relation between concurrently and previously measured bloo...

Journal: :Archives of general psychiatry 2000
J C de Groot F E de Leeuw M Oudkerk A Hofman J Jolles M M Breteler

BACKGROUND There is evidence for a vascular cause of late-life depression. Cerebral white matter lesions are thought to represent vascular abnormalities. White matter lesions have been related to affective disorders and a history of late-onset depression in psychiatric patients. Their relation with mood disturbances in the general population is not known. We investigated the relation between wh...

Journal: :Stroke 2008
Lisa Delano-Wood Norm Abeles Joshua M Sacco Christina E Wierenga Nikki R Horne Andrea Bozoki

BACKGROUND AND PURPOSE Associations between regional white matter lesion pathology and neuropsychological performance across the aging spectrum are not well understood and, to date, research has been largely contradictory and inconclusive. The current study set out to clarify some of the inconsistencies in the literature by relating volumetric analyses of white matter lesions (deep white matter...

Journal: :Brain : a journal of neurology 2002
F-E de Leeuw J C de Groot M Oudkerk J C M Witteman A Hofman J van Gijn M M B Breteler

White matter lesions are frequently found on cerebral MRI scans of elderly people and are thought to be important in the pathogenesis of dementia. Hyper tension has been associated with the presence of white matter lesions but this has been investigated almost exclusively in cross-sectional studies. We studied prospectively the association of these lesions with the duration and treatment of hyp...

Journal: :The Journal of Kansai Medical University 1989

Journal: :CNS Neuroscience & Therapeutics 2010

Journal: :British Journal of Psychiatry 1989

Journal: :Nature Reviews Neurology 2011

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