daraus auf fotomechanischem Wege (Fotokopie, Mikrokopie) oder auf andere Art zu vervielfaltigen,

Dr. Michael Zapf ist wissenschaftlicher Assistent an der Universität Kassel im Fachgebiet Verteilte Systeme. Seine Forschungsschwerpunkte liegen auf autonomen vernetzten Systemen und verteilt-kooperativer Informationsverarbeitung. Während seiner Promotionsphase an der Goethe-Universität Frankfurt/ Main war er im Forschungsfeld der mobilen und autonomen Softwareagenten tätig und spezialisierte s...

OBJECTIVE Previous work suggested that first-trimester exposure to tricyclic antidepressants or fluoxetine does not affect adversely child IQ and language development. However, many women need antidepressants throughout pregnancy to avoid morbidity and suicide attempts. Little is known about the fetal safety of tricyclic antidepressants and fluoxetine when taken throughout pregnancy. The goal o...

Tricyclic antidepressants have a long history in the treatment of headache. In 1964 Lance and Curran reported a better response to amitriptyline (30-75 mg/day) in chronic tension headache (n=280) compared with 11 other commonly used drugs (such as benzodiazepines, vasodilators, and sedatives). They also reported a placebo controlled crossover trial of 27 patients that showed clinically signific...

The authors report four cases of Monopolar Depressed patients who developed manic features for the first time while on tricyclic antidepressant therapy. The phenomenon is viewed as tricyclic antidepressant induced mania. The manic symptoms occurred late in therapy, with moderate doses of tricyclic antidepressants (125-150 mg per day) and were easily controlled with antipsychotic medication. Fac...