Children and adolescents suffering from anxiety disorders may require pharmacotherapy. Tricyclic antidepressants are often prescribed in these instances. Unfortunately, most clinical research analyzing the effectiveness of tricyclic antidepressants on anxiety disorders has focused exclusively on adult patients. This critical review examines those studies that have investigated the effects of tr...

‎let $d_{n,m}=big[frac{2n+1-sqrt{17+8(m-n)}}{2}big]$ and‎ ‎$e_{n,m}$ be the graph obtained from a path‎ ‎$p_{d_{n,m}+1}=v_0v_1 cdots v_{d_{n,m}}$ by joining each vertex of‎ ‎$k_{n-d_{n,m}-1}$ to $v_{d_{n,m}}$ and $v_{d_{n,m}-1}$‎, ‎and by‎ ‎joining $m-n+1-{n-d_{n,m}choose 2}$ vertices of $k_{n-d_{n,m}-1}$‎ ‎to $v_{d_{n,m}-2}$‎. ‎zhang‎, ‎liu and zhou [on the maximal eccentric‎ ‎connectivity ind...

Let $G$ be a connected graph on $n$ vertices. $G$ is called tricyclic if it has $n + 2$ edges, and tetracyclic if $G$ has exactly $n + 3$ edges. Suppose $mathcal{C}_n$ and $mathcal{D}_n$ denote the set of all tricyclic and tetracyclic $n-$vertex graphs, respectively. The aim of this paper is to calculate the minimum and maximum of eccentric connectivity index in $mathcal{C}_n$ and $mathcal{D}_n...

Tricyclic antidepressants have a long history in the treatment of headache. In 1964 Lance and Curran reported a better response to amitriptyline (30-75 mg/day) in chronic tension headache (n=280) compared with 11 other commonly used drugs (such as benzodiazepines, vasodilators, and sedatives). They also reported a placebo controlled crossover trial of 27 patients that showed clinically signific...

Correspondence BRiTISH 301 Tricyclic Antidepressants SIR,-I am worried by one sentence in the article on tricyclic antidepressants (13 April, p. 102): "Jaundice, which is very uncommon , is of the cholestatic type similar to that found in chlorpromazine." This is misleading. Jaundice is one of the more frequent side-effects reported from imipramine and imitrip-tyline, the most widely used membe...

background: tricyclic antidepressants (tcas) poisoning is the most common poisoning in the poisoning emergency department of noor hospital, isfahan, iran. the objective of this study was to compare qrs interval duration with ravr³3mm and r/savr³ 0.7 in predicting: serious complications of acute tca toxicity. methods and materials: this study was descriptive – analytic and prospective cohort. tc...

The synthetic route toward novel tricyclic, nitrogen-containing system is disclosed. Three compounds possessing structural features of 1,2,3,4-tetrahydroquinoxaline and decahydropyrido[3,4-b]pyrazine are synthesized starting from readily available precursors in six or seven steps, which the last three four steps respectively diastereoselective. Key reaction include N-acylation, Hofmann rearrang...