In agricultural harvesting processes, the infield logistics of transporting the crop from the harvesters' tanks to a street transporter at the field border with an unloading vehicle is challenging. The harvesters have to be unloaded while driving and in time to prevent the loss of expensive process time. The path planning for the unloading vehicle has to consider the unharvested area as a dynam...

This paper presents the BioShuttle platform as a delivery vehicle for transfer of contrast agents and genetic material into target cells, which can be followed by activation of the BioShuttle inside the target cell. Here, we present a transporter system and summarize the findings on transporter use in vivo and in vitro. The results here are limited to examples where cargoes (drugs, genetically ...

Primary pulmonary hypertension (PPH) is a lifethreatening disease that mostly affects young adults, more commonly women than men. It is characterized by vasoconstriction of the small pulmonary arteries, proliferation in all layers of the vessel wall, thrombosis-in situ, and inflammation. Serotonin (5-hydroxytryptamine, 5-HT) is thought to play a role in the pathogenesis of PPH, in part, because...

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Introduction: The overexpression of ATP-binding cassette (ABC) transporters, ABCB1 and ABCG2, are two the major mediators multidrug resistance (MDR) in cancers. Although multiple ABCG2 inhibitors have been developed some undergone evaluation clinical trials, none clinically approved. compound, MK-2206, an inhibitor protein kinases AKT1/2/3, is undergoing trials for treatment certain types cance...

PURPOSE The present study assessed the influence of L-DOPA administration on neostriatal dopamine (DA) transporter (DAT) binding in relation to motor and exploratory behaviors in the rat. METHODS Rats received injections of 5 mg/kg L-DOPA, 10 mg/kg L-DOPA or vehicle. Motor and exploratory behaviors were assessed for 30 min in an open field prior to administration of [(123)I]FP-CIT. Dopamine t...

Classification of combat vehicle types based on acoustic and seismic signals remains a challenging task due to temporal and frequency variability that exists in these passively collected vehicle indicators. This paper presents the results of exploiting the wavelet characteristic of projecting signal dynamics to an efficient temporal/scale (i.e. frequency) decomposition and extracting from that ...

although there are remarkable differences in drivers’ behavior as well as vehicles characteristics, road capacity estimationmethods in developing countries are same as developed ones. so, the discrepancy between the theoretical andpractical values of capacity is inevitable. although, capacity estimation methods can be classified based on numerousparameters, in developing countries, the availabi...