Parkinson’s disease is the second most common neurodegenerative disease, primarily affecting people of ages over 45-55 years, although young adults and even children can also be affected. The gold standard drug for the treatment of Parkinson’s disease is L-DOPA, but various studies have proved that the treatment with L-DOPA leads to the death of surviving dopaminergic neurons in the CNS. Hence ...

it is a common misconception that ayurvedic medicines (traditional indian system of medicine) are always safe. in fact, they also pose serious health risks either in the form of adverse reactions or in the form of drug interactions. over 80% of our population takes ayurvedic medicines. to evaluate the safety profile of tinospora cordifolia in healthy volunteers using a battery of haematological...

seed oils of passiflora edulis, jatropa curucas, tinospora cordifolia, sesbania grandiflora and sapindus laurifolia were investigated for their antihelmintic property against pheritima pasthuma. three concentrations (10, 50 and 100 mg/ml) of each oil were studied in the bioassay, which involved the determination of time of paralysis and time of death of the worm. sesbania grandiflora showed the...

BACKGROUND The current practice of ingesting phytochemicals for supporting the immune system or fighting infections is based on centuries-old tradition. Macrophages are involved at all the stages of an immune response. The present study focuses on the immunostimulant properties of Tinospora cordifolia extract that are exerted on circulating macrophages isolated from CCl(4) (0.5 ml/kg body weigh...

The Effect of tincture of Tinospora cordifolia was evaluated using onion root tip mitosis as the test system. The aqueous extract stimulated the mitotic activity significatory.

Karyotypic analysis of Tinospora cordifolia (Willd.) was carried out to determine the chromosomal classification by using “Aceto-orcine stain”. The plant is diploid with 2n=22 (18m+2Sm+2St) chromosomes and characterized in eleven pairs of chromosomes. The chromosomes are very short with a mean length 2.64 μm. and the total length of haploid complements was found 29.04 μm. The ideogram of Tinosp...

It is a common misconception that ayurvedic medicines (traditional Indian system of medicine) are always safe. In fact, they also pose serious health risks either in the form of adverse reactions or in the form of drug interactions. Over 80% of our population takes ayurvedic medicines. To evaluate the safety profile of Tinospora cordifolia in healthy volunteers using a battery of haematological...

The present study was conducted to evaluate the hepatoprotective activity of different extracts of Tinospora cordifolia against carbon tetrachloride (CCl4) induced liver damage in rats. The pet ether, ethanol and aqueous extracts of various parts of the plant such as leaf, stem and root were tested at the dose of 200mg/kg body weight orally using Wistar albino rats and Silymarin was given as re...