The introduction of imatinib mesylate (IM) has revolutionized the treatment of chronic myeloid leukemia (CML). Although experience is too limited to permit evidence-based evaluation of survival, the available data fully justify critical reassessment of CML management. The panel therefore reviewed treatment of CML since 1998. It confirmed the value of IM (400 mg/day) and of conventional allogene...

CGR is an effective method for visualizing any structural features if it is given as a sequence of elements [1,2] analyzed by the genomic signature appears as a powerful tool for investigating the mechanisms of DNA maintenance from which the DNA structure results. It would be necessary to understand the patterns they exhibit and to be able to interpret them in a biologically meaningful way [3]....

Desensitization of guanine nucleotide binding protein-coupled receptors is a ubiquitous phenomenon characterized by declining effector activity upon persistent agonist stimulation. The luteinizing hormone/choriogonadotropin receptor (LH/CGR) in ovarian follicles exhibits desensitization of effector adenylyl cyclase activity in response to the mid-cycle surge of LH. We have previously shown that...

In a previous study in dogs, the early removal of expanded polytetrafluoroethylene (ePTFE) membrane (2 weeks after placement) showed histomorphometric results (of new bone, cementum and periodontal ligament) similar to that obtained with membrane removal at 4 weeks after placement. This study evaluated the influence of early removal of an ePTFE membrane on the treatment of Class II furcation de...

Growth parameters such as leaf area (LA), total dry mass (TDM) production, crop growth rate (CGR), relative growth rate (RGR), and net assimilation rate (NAR) were compared in six varieties of mungbean under subtropical condition (24°8' N 90°0' E) to identify limiting growth characters for the efficient application of physiology breeding for higher yields. Results revealed that a relatively sma...

Similar to the chaos game representation (CGR) of DNA sequences proposed by Jeffrey (Nucleic Acid Res. 18 (1990) 2163), a new CGR of protein sequences based on the detailed HP model is proposed. Multifractal and correlation analyses of the measures based on the CGR of protein sequences from complete genomes are performed. The Dq spectra of all organisms studied are multifractal-like and suffici...

some pattern (information) in the DNA sequence Chaos game representation (CGR) of DNA (Goldman 1993). Goldman (1993) interpreted the sequences and linked protein sequences CGRs in a biologically meaningful way. All points from genomes was proposed by Jeffrey (1990) plotted within a quadrant must corresponding to suban d Yu et al. (2004), respectively. In this sequences of the DNA sequence that ...

Résumé Introduction: L’hémorragie du post-partum est la principale cause de morbi-mortalité maternelle dans le monde. La prise en charge est multidisciplinaire. La stratégie transfusionnelle est capitale jouant un rôle majeur dans le pronostic maternel. L’objectif de ce travail a été de déterminer le rapport PFC/CGR lors de la prise en charge des hémorragies graves du post-partum. Méthodes: Une...