A new protocol has been developed for trifluoromethylation of arenediazonium salts with moisture-sensitive CuCF3 (from fluoroform) in aqueous media. The reaction is governed by a radical mechanism, tolerates a broad variety of functional groups, and is applicable to the synthesis of complex, polyfunctionalized molecules.

A series of new 2,3,5-triaryl-substituted oxazolium and thiazolium salts are readily prepared by a Tf(2)O-mediated intramolecular cyclisation and their use as precursors for the synthesis of novel oxazol-4-ylidene and thiazol-4-ylidene rhodium complexes has been developed.

Monohydrochlorides of cis-2,5-diphenylpiperazine assume a chair conformation, while the corresponding dihydrochlorides assume a boat form regardless of the substituent(s) at the nitrogen atom.

Several liquid-liquid extraction systems containing vanadium {vanadium(IV) or vanadium(V)}, azoderivative of resorcinol {ADR: 4-(2-pyridylazo)-resorcinol (PAR) or 4-(2-thiazolylazo)-resorcinol (TAR)} and (phenylmethoxibis)tetrazolium salts {MBT: 3,3'-(3,3'-dimetoxy-4,4'-biphenylene)-bis(2,5diphenyl-2H-tetrazolium) chloride (Blue Tetrazolium, BT) or 3,3'-(3,3'-dimetoxy-4,4'-biphenylene)bis[2,5-d...

The use of tetrazolium salts for metabolic studies has been dismissed on the basis of their poor penetration into fresh tissue slices. In view of the fact that the penetration of these compounds can be visualized, it was felt that knowledge of the factors involved would be important. Factors, known to influence the penetration of oxygen, were examined with respect to the tetrazolium salts. The ...