conclusions our findings indicate that fullerenol nanoparticles decrease the brain infarction through enhancement of the sod activity during cerebral ischemia-reperfusion injury. results occlusion of mca induced considerable infarction and lesion in ischemic hemispheres of control ischemic rats (527 ± 59 mm3) in accompany with a decrease in the glutathione content (45%), and sod activity (29%) ...

"Pro captu lectoris habent sua fata libelli" (" According to the capabilities of the reader, books have their destiny ") Terentianus Maurus, 2 nd century roman grammarian

Amyotrophic lateral sclerosis is a rapidly progressing fatal neurodegenerative disease characterized by the presence of protein inclusions within affected motor neurons. Endoplasmic reticulum stress leading to apoptosis was recently recognized to be an important process in the pathogenesis of sporadic human amyotrophic lateral sclerosis as well as in transgenic models of mutant superoxide dismu...

objective(s): to investigate the chronopharmacological effects of growth hormone on executive function and the oxidative stress response in rats. materials and methods: fifty male wistar rats (36-40 weeks old) had ad libitum access to water and food and were separated into four groups: diurnal control, nocturnal control, diurnal gh-treated, and nocturnal gh-treated animals. levels of cu, zn sup...

Dissociation of superoxide dismutase 1 dimers is enhanced by glutathionylation, although the dissociation constants reported to date are imprecise. We have quantified the discreet dissociation constants for wild-type superoxide dismutase 1 and six naturally occurring sequence variants, in their unmodified and glutathionylated forms, at the ratios expressed. Unmodified superoxide dismutase 1 var...

conclusions the administration of 75 mg/kg/day cinnamon significantly increased the sperm population, motility and viability, which supports the theory that in mammalians, cinnamon has a beneficial effect on spermatogenesis. results sperm quality parameters, total serum testosterone, sod, cat, and gpx levels were significantly increased in the cinnamon group in comparison to controls (p < 0.05)...