Background: Cell-mediated immunity (CMI) plays an important role in resistance against leishmaniasis. Leishmanin test (Montenegro skin test) is a method in evaluation of immune system reaction against cutaneous leishmaniasis. The TDR/WHO reference Leishmanin produced by the Pasteur Institute of Iran is used worldwide. Two other antigens produced by Razi Serum Institute of Iran, Killed Leishmani...

Cell-mediated immunity (CMI) plays an important role in resistance against leishmaniasis. Delayed-type hypersensitivity (DTH) reaction measured by skin testing is a practical method of evaluation of CMI and is used as an aid to diagnosis and for epidemiological assessment of exposure to leishmanial infection. Skin testing in leishmaniasis, generally known as Montenegro or leishmanin test, r...

delayed-type hypersensitivity (dth) reaction measured by skin testing is an important indicator for evaluation of cellular immune response in leishmaniasis. skin testing in leishmaniasis, known as leishmanin or montenegro test, is used normally for immunoepidemiological studies and for diagnosis. in cutaneous leishmaniasis (cl), the skin test is positive during the active phase of disease and r...

BACKGROUND The inflammatory response is prominent in the pathogenesis of dermal leishmaniasis. We hypothesized that regulatory T cells (Tregs) may be diminished in chronic dermal leishmaniasis (CDL) and contribute to healing during treatment. METHODOLOGY/PRINCIPAL FINDINGS The frequency and functional capacity of Tregs were evaluated at diagnosis and following treatment of CDL patients having...

cell-mediated immunity (cmi) plays an important role in resistance against leishmaniasis. delayed-type hypersensitivity (dth) reaction measured by skin testing is a practical method of evaluation of cmi and is used as an aid to diagnosis and for epidemiological assessment of exposure to leishmanial infection. skin testing in leishmaniasis, generally known as montenegro or leishmanin test, requi...

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The objective of this study was to evaluate the magnitude of le ishmaniasis in the study area and to assess the role of demographic and nutritional status in the disease transmission. It was a prospective cohort study on leishmaniasis. It was conducted in 3 villages in West of Sudan. Leishmanin skin test (LST) was assessed as an epidemiological tool in a sub-clinical focus of leishmania in Suda...

A 46 year-old man, agriculturist, presented with an eight-month history of skin lesions all over his body. Patient did not refer systemic symptoms; however he was a heavy alcoholic drinker until three months after the beginning of disease, when he stopped drinking. Physical exam was inconspicuous except for multiples skin lesions (papular, crusted or ulcerated) on face, trunk (Panels A and B), ...

In a number of papers since 1952 Sagher and associa tes (18. 27. 29-35 ) have called attention to a specific tissue response of the noninvolved skin of lepromatous leprosy on intradermal injection with various agents. Tuberculin , leishmanin , milk, p eptone and living leishmanial leptomonads elicited a prelepromatous or lepromatous infiltration, usually without bacilli, at the site of the inje...