نتایج جستجو برای: signaling molecules

تعداد نتایج: 471054  

The immune system of mammalian organisms undergoes alterations that may account for an increased susceptibility to certain infections, autoimmune diseases, or malignancies. Well characterized are age related defect in T cell functions and cell mediated immunity. Although it is well established that the functional properties of T cells decrease with age, its biochemical and molecular nature is...

Hossein Mostafavi, Mahmoud Reza Hadjighassem, Maryam Soleimannejad, Mohammad Taghi Joghataei, Mojtaba Khaksarian, Raheleh Gholamzadeh, Sadegh Yoosefee, Sanam Seifollahi Bahnamiri,

Introduction: Malignant astrocytic gliomas are the most common and lethal brain malignancies due to their refractory to the current therapies. Nowadays, molecular targeted therapy has attracted great attention in treatment of glioma. Connexin 43 (Cx43) and micro ribonucleic acid- 21(miR-21) are among molecules that are involved in glioma development and progression. These molecules showed...

Journal: :Current Opinion in Neurobiology 2008

Journal: :iranian biomedical journal 0
محمد علی پهلوانی mohammad a. pahlavani

the immune system of mammalian organisms undergoes alterations that may account for an increased susceptibility to certain infections, autoimmune diseases, or malignancies. well characterized are age related defect in t cell functions and cell mediated immunity. although it is well established that the functional properties of t cells decrease with age, its biochemical and molecular nature is p...

Journal: :cell journal 0
ali fathi shahram eisa-beygi hossein baharvand

signaling in pluripotent stem cells is a complex and dynamic process involving multiple mediators, finely tuned to balancing pluripotency and differentiation states. characterizing and modifying the necessary signaling pathways to attain desired cell types is required for stem-cell applications in various fields of regenerative medicine. these signals may help enhance the differentiation potent...

Journal: :basic and clinical neuroscience 0
hossein mostafavi zanjan, iran mojtaba khaksarian khorramabad, iran mohammad taghi joghataei tehran, iran sadegh yoosefee tehran, iran mahmoud reza hadjighassem tehran, iran maryam soleimannejad

introduction: malignant astrocytic gliomas are the most common and lethal brain malignancies due to their refractory to the current therapies. nowadays, molecular targeted therapy has attracted great attention in treatment of glioma. connexin 43 (cx43) and micro ribonucleic acid- 21(mir-21) are among molecules that are involved in glioma development and progression. these molecules showed poten...

Journal: :iranian journal of immunology 0
masoumeh varedi department of physiology, medical school, shiraz university of medical sciences, shiraz, iran

interferons (ifns) are a family of small regulatory glycoproteins that play a central role in the defense against viral infections. although ifns have been initially discovered as antiviral factors, today they are known as an integral part of the cytokine network that affect a wide range of biological processes. ifns exert their pleiotropic effects through their multisubunit cell surface recept...

Journal: :Journal of Molecular Endocrinology 2008

Journal: :Clinics in Laboratory Medicine 2019

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