نتایج جستجو برای: sesquitepene coumarins

تعداد نتایج: 1764  

2014
Venugopala K. Narayanaswamy Raquel M. Gleiser Kabange Kasumbwe Bandar E. Aldhubiab Mahesh V. Attimarad Bharti Odhav

Mosquitoes are the major vectors of parasites and pathogens affecting humans and domestic animals. The widespread development of insecticide resistance and negative environmental effects of most synthetic compounds support an interest in finding and developing alternative products against mosquitoes. Natural coumarins and synthetic coumarin analogues are known for their several pharmacological ...

Journal: : 2023

Background: Coumarins and their derivatives excel in chemical diversity, coupled with a wide variety of biological potentials, tend to be beneficial the health human body. One these that has sparked attention medicinal chemistry specialists recent decades is benzo-fused coumarins, which have demonstrated potential as antioxidants, antimicrobials, antidiabetics, antithrombotics, many more. Objec...

Journal: :Molecules 2016
Gilbert Kirsch Ahmed Bakr Abdelwahab Patrick Chaimbault

In this review, we will present the different aspects of coumarins and derivatives, from natural origins or synthetically prepared, and their action on inflammation. Coumarins and also furo- and pyranocoumarins are found in many different plants. These compounds are very often investigated for antioxidant properties. Other biological properties are also possible and anti-inflammation activity i...

2008
M. C. Ballesta-Acosta M. J. Pascual-Villalobos B. Rodríguez

Worms are becoming difficult pests to control since many insecticides are now forbidden and the present alternatives are insufficiently effective. Antifeedants of plant origin may have potential against such pests. In this work, several diterpenoids, flavones and coumarins extracted from plants were assayed as antifeedant agents against Spodoptera littoralis larvae. Among these compounds, four ...

Journal: :Molecules 2009
Brian D Wagner

Coumarins, as a family of molecules, exhibit a wide range of fluorescence emission properties. In many cases, this fluorescence is extremely sensitive to the local environment of the molecule, especially the local polarity and microviscosity. In addition, coumarins show a wide range of size, shape, and hydrophobicity. These properties make them especially useful as fluorescent probes of heterog...

Journal: :Chemical communications 2015
Wei Wei Jiangwei Wen Daoshan Yang Mengyuan Guo Yingying Wang Jinmao You Hua Wang

A novel and metal-free procedure has been developed for the construction of 3-sulfonated coumarins via the direct difunctionalization of alkynoates with sulfonylhydrazides. The present protocol, which simply utilizes TBAI as the catalyst and TBHP as the oxidant, provides a convenient and highly efficient approach to construct a series of sulfonated coumarins with high regioselectivity and good ...

Journal: :Circulation 2000
J M ten Berg J C Kelder M J Suttorp E G Mast E Bal S M Ernst F W Verheugt H W Plokker

BACKGROUND Coronary angioplasty frequently creates a thrombogenic surface, with subsequent mural thrombosis that may lead to acute complications and possibly stimulates the development of restenosis. Whether coumarins can prevent these complications is unclear. The objective of this open, randomized trial was to assess the clinical effect of coumarins started before coronary angioplasty and con...

2017
Vanessa Gonzalez-Covarrubias Javier Urena-Carrion Beatriz Villegas-Torres J. Eduardo Cossío-Aranda Sergio Trevethan-Cravioto Raul Izaguirre-Avila O. Javier Fiscal-López Xavier Soberon

Coumarins are widely prescribed worldwide, and in Mexico acenocumarol is the preferred form. It is well known that despite its efficacy, coumarins show a high variability for dose requirements. We investigated the pharmacogenetic variation of 110 genes in patients receiving acenocumarol using a targeted NGS approach. We report relevant population differentiation for variants on CYP2C8, CYP2C19,...

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 1999
O Kayser H Kolodziej

The antibacterial activity of a series of simple coumarins was evaluated against 8 microorganisms, including three Gram-positive (Staphylococcus aureus, beta-hemolytic Streptococcus and Streptococcus pneumoniae) and five Gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis and Haemophilus influenzae), using the microdilution broth method. Th...

2000
Klaus Peter Latté Oliver Kayser Herbert Kolodziej

Z. Naturforsch. 55c, 5 2 8 -5 3 3 (2000); received April 5/April 20. 2000 Pelargonium Species, Umckaloabo, Coumarins, Oxygenation Pattern The coumarin patterns of Pelargonium sidoides DC. and Pelargonium reniforme CURT., forming the origin of the herbal medicine “umckaloabo”, were analysed and compared for therapeutic equivalence. For both species, members of triand tetraoxygenated coumarins al...

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