Objective: Type 2 diabetes mellitus (T2DM) is a multifactorial disorder with various disturbances in biochemical processes such as antioxidant status and lipid peroxidation. The aim of present study was evaluation of the oxidative stress markers in saliva of T2DM patients. Materials and Methods: In this study, 80 (40 T2DM and 40 control) individuals were assessed. The salivary total antioxidan...

Periodontal disease is a common chronic adult condition. The bacterium Porphyromonas gingivalis has been implicated in the aetiology of this disease, which causes destruction of the connective tissue and bone around the root area of the tooth. It has been observed that invading P. gingivalis bacteria trigger the release of cytokines such as interleukin 8 and tumour necrosis factor a, leading to...

The aim of this cohort study was to determine whether periodontitis and gingivitis are associated with impaired salivary antioxidant status and increased oxidative injury. One hundred and twenty-nine patients attending a routine dental check-up were recruited for the study. Periodontal disease status was characterized using the Community Periodontal Index of Treatment Needs (CPITN) system. Tota...

background and aims. cigarette smoke can induce oral cancer by its free radicals and oxidative damage. salivary antioxidants system is believed to have an important role in defense mechanisms against oxidative stress. this study was compared total antioxidant capacity (taoc) of saliva in smokers and nonsmokers. materials and methods. in this cross-sectional study, 30 male smokers with mean age ...

The effect of smoking is in our days a serious global public health problem of major concern. Incidence of oral squamous cell carcinoma (SCC) in cigarette smokers is four to seven times higher than in nonsmokers. There is a constant and direct attack of various cigarette smoke constituents on the oral epithelial cells, which gradually accumulate and cause malignant transformation. Saliva is the...

Background Pregnancy is considered a stressful event, results in higher levels of oxidative stress and considerable changes in physiological and metabolic functions such as gestational diabetes mellitus (GDM). Due to the cumulative effect of antioxidants and considering the controversies in this area, this study was undertaken to investigate the total antioxidant capacity (TAC) of saliva in pre...

AIM Our goal was to investigate associations among scaling-stimulated changes in salivary antioxidants, oral-health-related behaviors and attitudes, and periodontal treatment outcomes. MATERIALS AND METHODS Thirty periodontitis patients with at least 6 pockets with pocket depths of >5 mm and more than 16 functional teeth were enrolled in the study. Patients were divided into three groups: an ...

Background and Objective: Oral cancer is one of the 10 most common cancers in the world and its global outbreak is increasing. Saliva assessment is one of the non-invasive diagnostic methods for this cancer. The aim of the study was to achieve a comprehensive conclusion about changes in salivary antioxidants in patients with squamous cell carcinoma of the mouth (OSCC). Materials and Methods: I...

Background: Oral cancer is among the 10 most common cancers worldwide with an increasing global incidence. Compromised antioxidant defense system plays a role in occurrence of cancer. This study evaluated the salivary antioxidant level of oral cancer patients compared to a control group. Patients and Methods: This case-control study was conducted on 22 oral squamous cell carcinoma patients pre...