Background: Simvastatin is a widely used medication in cardiac care. Here we evaluate the role of ATP sensitive potassium (KATP) channels in simvastatin induced renal protection after renal ischemia/reperfusion (I/R) injury.
Methods: A total of 81 male Wistar rats, were treated with simvastatin (10 and 20mg/kg/day gavage, one week). Some groups received glibenclami...