introduction: the objective of the present study is to investigate the relationship between the familial history of digestive system cancers and development of gastric cancer. methods: in this case-control study conducted in 2012, 84 patients with a definite diagnosis of gastric cancer, diagnosed using endoscopy and pathological study of biopsies, were compared with 84 people with the same age ...

BACKGROUND Late-onset and solitary recurrence of gastric signet ring cell (SRC) carcinoma is rare. We report a successful surgical resection of late solitary locoregional recurrence after curative gastrectomy for gastric SRC carcinoma. CASE REPORT The patient underwent total gastrectomy for advanced gastric carcinoma at age 52. Seven years after the primary operation, he visited us again with...

leptomeningeal carcinomatosis (lmc) from gastrointestinal cancer would be rare. a 56-years old man with complaint of dyspepsia and histopathologic examination of the biopsy specimens has shown: adenocarcinoma. at the end of adjuvant chemo radiation therapy, the patient has affected by headache and mild confusion. in cerebrospinal fluid (csf) cytology, a plenty of malignant cells have seen and u...

The mechanism of abscopal effect is becoming clear by the progress of cancer immunology. A 54-year-old male with recurrent gastric cancer presented an abscopal effect after radiotherapy with concurrent adoptive T-cell immunotherapy (immunoradiotherapy). Immunoradiotherapy has potential to induce abscopal effect by strengthening systemic antitumor immunity even in recurrent cancer.

Hereditary diffuse gastric cancer (HDGC) is an inherited form of gastric cancer that carries a poor prognosis. Most HDGCs are caused by an autosomal dominant genetic mutation in the CDH1 gene, which carries a 70%-80% lifetime risk of gastric cancer. Given its submucosal origin, endoscopic surveillance is an unreliable means of early detection, and prophylactic gastrectomy is recommended for CDH...

introduction: esophageal and gastric cancers are among the most common cancers in iran. usually survival of these cases is poor despite of treatment. here we studied outcome of these cases in our center to have an estimation of general prognosis of patients. methods: in this retrospective study, we reviewed the data of patient's files before treatment, including cancer stage at diagnosis, types...

PURPOSE Palliative chemotherapy for patients with recurrent or metastatic gastric cancer has been shown to have a survival benefit. Docetaxel monotherapy has achieved appreciable results for treating gastric cancer. We investigated the clinical efficacy and feasibility of a docetaxel and cisplatin combination regimen for patients suffering with recurrent or metastatic gastric cancer. MATERIAL...

BACKGROUND Follow-up endoscopy after total gastrectomy for gastric cancer is commonly performed without there being any definite evidence of clinical relevance. Therefore, we investigated the role of the upper endoscopic examinations after total gastrectomy for gastric cancer. METHODS The medical records of 212 early gastric cancer (EGC) patients and 622 advanced gastric cancer (AGC) patients...

BACKGROUND The aim of the present study was to determine the suitable postoperative management of patients with gastric cancer. PATIENTS AND METHODS A total of 161 patients with gastric cancer who developed recurrence after curative resection were reviewed retrospectively to investigate the clinicopathological characteristics of recurrence in subgroups classified according to the Japanese Cla...