نتایج جستجو برای: rebound activity
تعداد نتایج: 1139383 فیلتر نتایج به سال:
We present a computational model of a thalamocortical relay neuron for exploring basal ganglia thalamocortical loop behavior in relation to Parkinson's disease and deep brain stimulation (DBS). Previous microelectrode, single-unit recording studies demonstrated that oscillatory interaction within and between basal ganglia nuclei is very often accompanied by synchronization at Parkinsonian rest ...
A number of theories have been reported on post saccade phenomenon describing dynamic overshoot, glissadic overshoot and undershoot, and undershoot, all naturally and frequently occurring saccadic eye movements. Electrophysiological evidence for post-inhibitory rebound burst firing activity during saccadic eye movements is prevalent in the literature. However, the cause for the phenomenon is no...
This paper presents a computational model of a thalamocortical (TC) relay neuron that is used to explore the behaviour of the basal-ganglia thalamocortical loop in relation to Parkinson’s disease and deep brain stimulation. Low frequency oscillations associated with Parkinson’s disease impair thalamic processing by generating rebound action potentials. In the model the thalamocortical cell rece...
Reciprocally connected glutamatergic subthalamic and GABAergic globus pallidus neurons have recently been proposed to act as a generator of low-frequency oscillatory activity in Parkinson's disease. To determine whether GABA(A) receptor-mediated synaptic potentials could theoretically generate rebound burst firing in subthalamic neurons, a feature that is central to the proposed oscillatory mec...
On withdrawal of inhalation of nitric oxide (INO) administered after lung injury, pulmonary artery pressure (PAP) and arterial oxygen tension (Pa(O(2))) may deteriorate more than before INO (rebound response). In this study, we investigated the possible roles of endothelin (ET)-1 and nitric oxide (NO) synthase (NOS) activity in the short rebound reaction to short-term inhalation of NO. Twenty-s...
Succinate-CoA ligase (SUCL) is a heterodimer enzyme composed of Suclg1 α-subunit and a substrate-specific Sucla2 or Suclg2 β-subunit yielding ATP or GTP, respectively. In humans, the deficiency of this enzyme leads to encephalomyopathy with or without methylmalonyl aciduria, in addition to resulting in mitochondrial DNA depletion. We generated mice lacking either one Sucla2 or Suclg2 allele. Su...
Rebound disease following cessation of disease modifying treatment (DMT) has been reported in people with both relapsing and progressive multiple sclerosis (pwRMS, pwPMS) questioning strict separation between these two phenotypes. While licensed DMT is available for pwRMS to counter rebound disease, no such option exists for pwPMS. We report on a pwPMS who developed rebound disease, with 45 Gad...
BACKGROUND Integration of afferent somatosensory input with motor-cortex output is essential for accurate movements. Prior studies have shown that tactile input modulates motor-cortex excitability, which is reflected in the reactivity of the ∽ 20-Hz motor-cortex rhythm. ∽ 20-Hz rebound is connected to inhibition or deactivation of motor cortex whereas suppression has been associated with increa...
Introduction:The aim of this study is to compare significant post-phototherapy bilirubin rebound in two groups of neonates, with two levels of bilirubin, at discontinuation of phototherapy. Materials and Methods:One hundred and fifteen neonates ≥35 weeks of gestationl age (GA), admitted due to hyperbilirubinemia in the Neonatal Ward of Valiasr Hospital, were randomly divided into two groups: gr...
OBJECTIVE Performing foot motor imagery is accompanied by a peri-imagery ERD and a post-imagery beta ERS (beta rebound). Our aim was to study whether the post-imagery beta rebound is a suitable feature for a simple "brain switch". Such a brain switch is a specifically designed brain-computer interface (BCI) with the aim to detect only one predefined brain state (e.g. EEG pattern) in ongoing bra...
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