Novel quinoxaline-based organic sensitizers using vertical (RC-21) and horizontal (RC-22) conjugation between an electron-donating triphenylamine unit and electron-accepting quinoxaline unit have been synthesized and used for dye-sensitized solar cells (DSSCs), leading to the relatively high power conversion efficiencies of 3.30 and 5.56% for RC-21 and RC-22, respectively. This result indicates...

Herein we report the design and synthesis of 6-amino-quinoxaline-alkynyl derivatives, which were evaluated for their anti-cancer properties against MCF-7 breast cancer cells. A total 11 amino-quinoxaline compounds identified by molecular docking from a library over 100 compounds, to be potential aromatase (CYP19A1) inhibitors. MD simulations shed more light on equilibration stabilities enzyme-l...

9,10-Quinoxaline-fused porphycenes 1a-H₂ and 1b-H₂ were synthesized by intramolecular McMurry coupling. As a result of the annulation of the quinoxaline moiety on the porphycene skeleton, 1a-H₂ and 1b-H₂ display absorption and fluorescence in the near infra-red (NIR) region. Additionally, the quinoxaline moieties of 1a-H₂ and 1b-H₂ act as electron-withdrawing groups, introducing lower reduction...

Quinoxaline 1,4-dioxide (4) is the historical prototype for modern heterocyclic N-oxide antitumor agents such as 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine, 1) and 3-amino-2-quinoxalinecarbonitrile 1,4-dioxide (11). Early experiments in bacterial cell lines suggested that enzymatic, single-electron reduction of quinoxaline 1,4-dioxides under low-oxygen (hypoxic) conditions leads to D...

A new Z' = 1 crystal structure of quinoxaline (or 1,4-diaza-naphthalene), C(8)H(6)N(2), with one-fifth the volume of the earlier known Z' = 5 structure was obtained by means of an in situ cryocrystallization technique.

We evaluated the effects of 23 insecticides and 9 fungicides on mite Neoseiulus barkeri（Hughes）collected from melon gerbera greenhouses. The nitenpyram, acetamiprid, flufenoxuron, chlorantraniliprole, pyridalyl, acequinocyl, cyenopyrafen, cyflumetofen, pyflubumide, fungicide flutianil＋mepanipyrim had no effect survival fecundity adult females. In contrast, spinosad, spinetoram, abamectin, emame...

3-(l-Halo-2-oxo-2-substitutedethyl)-2(lH)quinoxalinones, Furo[2,3-b]quinoxalines An efficient method for the synthesis of furo[2,3-b]quinoxalines has been devised. Thus, 3-halo-2-arylfuro[2,3-b]quinoxalines, 5a-5c were synthesized by the action of conc. H2SO4 on 3-(l-halo-2-oxo-2-arylethyl)-2(lH)quinoxalinones, 3b, 3c and 3f respectively. When 3-(1 -halo-2-oxo-2-substitutedethyl)-2(1H)quinoxali...

• HPPD is one of the most promising targets for new herbicides. A family novel inhibitors based on triketone-quinoxaline scaffold was designed and synthesized. One particular product (7d) gave highest inhibition newly synthesized derivatives. Triketone-quinoxaline derivatives provide a useful molecular discovery HPPD-inhibiting </ItemCont...

The title compound, C(28)H(22)N(4), is the unexpected by-product of the reaction of 2-hydroxy-acetophenone and 1,2-diamino-benzene under iodine catalysis, during which a carbon-carbon σ-bond between two quinoxaline units was formed. Although a fully oxidized title compound should sterically be possible, only one quinoxaline ring is fully oxidized while the second ring remains in the reduced for...

The title compound, C(18)H(8)Cl(4)N(4), exists in a cis configuration with respect to the bridging C=C bond. The two essentially planar quinoxaline ring systems [maximum deviations = 0.012 (1) and 0.022 (1) Å] are inclined at an angle of 59.84 (3). In the crystal, adjacent mol-ecules are linked into chains propagating along [001] via inter-molecular C-H⋯N hydrogen bonds. Weak inter-molecular π-...