BACKGROUND We examined prospectively which of the four blood pressure (BP) components (systolic BP [SBP], diastolic BP [DBP], pulse pressure [PP], and mean arterial pressure [MAP]) was best in predicting the risk of proteinuria. METHODS This prospective study included 9341 non-diabetic Japanese middle-aged men who had no proteinuria and an estimated glomerular filtration rate ≥60 mL/min/1.73 ...

OBJECTIVE The present study investigates the relationship between BMI and all-cause mortality among middle-aged and older adults with or without pre-existing diseases. DESIGN A population-based cohort study. SETTING The Taiwan Longitudinal Study on Aging is a nationwide prospective cohort study comprising a representative random sample of middle-aged and older adults. The study period was 1...

AIM The purpose of this prospective cohort study is to examine whether cognitive decline is an independent predictor of new long-term care insurance (LTCI) requirement certifications in Japan. METHODS A total of 5,765 community-dwelling older Japanese adults who, at baseline, were independent in terms of their activities of daily living participated in this study and were followed up for 18 m...

INTRODUCTION Simultaneous use of contraceptive hormones and anti-retroviral therapy (ART) may theoretically lessen the effectiveness of both. Women on ART need assurance that hormonal contraception is safe and effective. The sub-dermal implant is an ideal product to study: low and steady progestin release and no adherence uncertainties. We sought to determine if the medications' effectiveness i...

BACKGROUND Hormone therapy has been shown to increase risk of ischemic stroke in women. Plant-derived estrogens, particularly soy isoflavones, are known to have some estrogenic effects and have been marketed as natural alternatives to hormone therapy. Concerns have been raised about whether high isoflavone exposure may be related to ischemic stroke risk as well. OBJECTIVE We examined the diet...

background: coffee is implicated in the susceptibility to several cancers. however, the association between coffee and lymphoma remains unclear. this meta-analysis aimed to assess quantitatively the association between coffee and the incidence of lymphoma. methods: a literature search was performed for cohort and case-control studies published using pubmed, cochrane, and embase databases. studi...

  Background: Improvement of assisted reproductive technique (ART) results in higher pregnancy rates from positive Beta HCG to take home baby statistics. Despite developments in culture media allowing blastocyst stage transfer, some centers apply second, third and sometimes fourth day post injection for embryo transfer. This study aimed to compare their reproductive outcomes.   Methods : This p...

Background: Metabolic syndromes have been identified as a major risk factor for people with cardiovascular disease. Metabolic syndromes are defined as a range of conditions including waist-fat, abdominal obesity, high blood pressure, diabetes, high triglycerides, and HDL. Considering the importance of controlling metabolic syndrome, the research study subject with the mentioned aim is so import...

objective: there are various attempts to confirm variables that could predict postpartum depression in advance. this study determined antenatal risk factors for postpartum depression in women at risk of developing this disorder. methods: a prospective cohort study was conducted with 2279 eligible women who attended at mazandaran province’ primary health centers from 32-42 weeks of pregnancy to ...