statement of problem: avulsion is one of the most serious emergencies in dental office. avulsed teeth should be stored in a medium that supports the periodontal ligament cells viability. in some clinical situations, preserving media, contained growth factors and mitogenic products may be used for repair of traumatized (periodontal ligament) tissues. it has been previously reported that levodopa...

The major goal of periodontal therapy is periodontal regeneration including regeneration of alveolar bone, cementum and periodontal ligament fibres. Recapitulation of embryology shows the importance of Hertwig's epithelial root sheath (HERS), involved in cementogenesis and root formation. The remnants of these cells are found in normal periodontal ligament as the epithelial cell rests of Malass...

Using a model of experimental occlusal trauma in mice, we investigated cytological kinetics of periodontal ligament by means of histopathological, immunohistochemical, and photographical analysis methods. Periodontal ligament cells at furcation areas of molar teeth in the experimental group on day 4 showed a proliferation tendency of periodontal ligament cells. The cells with a round-shaped nuc...

The spatial distribution of dendritic cells, macrophages, and their respective precursor cells in the periodontal ligament of rat molars was examined by means of ACPase enzyme histochemistry and immunohistochemistry. Intense reactions for ACPase were localized in both the multinucleated-and mononucleated cells of the periodontal ligament located exclusively in the portions of physiological bone...

BACKGROUND We previously demonstrated that 25-hydroxyvitamin D(3), the precursor of 1α,25-dihydroxyvitamin D(3), is abundant around periodontal soft tissues. Here we investigate whether 25-hydroxyvitamin D(3) is converted to 1α,25-dihydroxyvitamin D(3) in periodontal soft tissue cells and explore the possibility of an autocrine/paracrine function of 1α,25-dihydroxyvitamin D(3) in periodontal so...

Periodontal disease is a chronic and irreversible disease that affects the supporting tissue of the teeth (gums, alveolar bone, cementum and periodontal ligament). The disease is often divided into two conditions: gingivitis and periodontitis. Gingivitis is inflammation of the gingiva, while periodontitis is inflammation of non-gingival tissue: periodontal ligament and alveolar bone (Harvey CE,...

We present mathematical models, computational algorithms and software, which can be used for prediction of results of prosthetic treatment. More interest issue is biomechanics of the periodontal complex because any prosthesis is accompanied by a risk of overloading the supporting elements. Such risk can be avoided by the proper load distribution and prediction of stresses that occur during the ...

OBJECTIVE Considering that periodontal ligament simulation may influence the stress distribution over teeth restored with intraradicular retainers, this study aimed to assess the combined effect of mechanical cycling and periodontal ligament simulation on both the bond strength between fiber posts and root dentin and the fracture resistance of teeth restored using glass fiber posts. MATERIAL ...

BACKGROUND Understanding of viscoelastic behaviour of a periodontal membrane under physiological conditions is important for many orthodontic problems. A new analytic model of a nearly incompressible viscoelastic periodontal ligament is suggested, employing symmetrical paraboloids to describe its internal and external surfaces. METHODS In the model, a tooth root is assumed to be a rigid body,...

INTRODUCTION Young's modulus (E) and Poisson's ratio (v) of the periodontal ligament are needed in a finite element analysis for investigating the biomechanical behavior of a tooth, periodontal ligament, and bone complex. However, large discrepancies in E (0.01-1,750 MPa) and v (0.28-0.49) were reported previously. The objective of this study was to narrow the ranges and to provide equivalent E...