Peptic ulcer disease (PUD) is one of the most commonly encountered gastroenterologic diseases in Korea. The trend in diagnosis and treatment of PUD in Korea has changed in the past decade with the introduction of endoscopy and potent acid suppressants such as proton pump inhibitors. The discovery of Helicobacter pylori has opened a new era for the understanding of pathogenesis and management of...

BACKGROUND Peptic ulcer disease is one of the most common diseases prevalent in developing country like Nepal and with availability of endoscopy there have been increase in diagnosis and therapeutic use of endoscopy. OBJECTIVE The aim of this study is to investigate the prevalence of peptic ulcer disease in patient who came for upper gastrointestinal endoscopy in Kathmandu Medical College Tea...

BACKGROUND Diagnoses of peptic ulcer are registered in the Danish National Patient Registry (DNPR) for administrative as well as research purposes, but it is unknown whether the coding validity depends on the location of the ulcer. OBJECTIVE To validate the International Classification of Diseases, 10th revision diagnosis codes of peptic ulcer in the DNPR by estimating positive predictive val...

BACKGROUND: During Ramadan, the 9 month in the Hijri lunar calendar, healthy adult Muslims are obliged to fast from sunrise to sunset. The fast of Ramadan has significant health effects and is the most commonly researched religious fasting. In this study, we will investigate available findings on the effects of Ramadan fasting on gastrointestinal (GI) signs, symptoms, and diseases. METHODS: We ...

PURPOSE Emergency operations for perforated peptic ulcer are associated with a high incidence of postoperative complications. While several studies have investigated the impact of perioperative risk factors and underlying diseases on the postoperative morbidity after abdominal surgery, only a few have analyzed their role in perforated peptic ulcer disease. The purpose of this study was to deter...

1.1 Background Peptic ulcer disease (PUD) had a tremendous effect on morbidity and mortality until the last decades of the 20th century. Development of new effective and potent acid suppressants and the discovery of Helicobacter pylori (H. pylori) are two important steps that caused a reduction in the prevalence of peptic ulcer. With the discovery of H. pylori, causes, pathogenesis and treatmen...

INTRODUCTION Limited data currently exists regarding the diagnostic indicators of peptic ulcer perforation for early detection among patients in Thailand. Delayed diagnosis and treatment for an ulcer can be life-threatening, resulting in shock or death. OBJECTIVE To determine the diagnostic indicators of peptic ulcer perforation. MATERIAL AND METHODS A cohort study was conducted in a tertia...

BACKGROUND & AIM The important role of IL-17 in inflammatory response to Helicobacter pylori (H. pylori) colonization has been indicated. We investigated the associations between gastro-duodenal diseases and polymorphisms of IL17A (rs2275913 G>A) and IL17F (rs763780 T>C). METHODS The study was performed in 548 subjects (363 controls and 185 peptic ulcer cases). The multiplex PCR-SSCP method w...

This study was conducted to determine the prevalence of Helicobacter pylori (H. pylori) and its associated factors among patients with peptic ulcer disease in Taiping Hospital. Consecutive peptic ulcer disease patients who had undergone esophagogastro-duodenoscopy were included. The H. pylori status was assessed by the rapid urease test. We excluded those who had active bleeding, a perforated p...

background : data concerning the information on the prevalence and association of the helicobacter pylori cytotoxinassociated gene a (caga) with disease is still controversial. the aim of this study was to isolate and identify h. pylori by culture methode from biopsy specimens and its relationship with associated diseases by molecular techniques (pcr). materials and methods: gastric biopsy spec...