A cell line derived from a murine sarcoma virus (Moloney pseudotype)-induced tumor has been established. It retains oncogenicity, releases both sarcoma and leukemia viruses, and has virus-induced cellular antigens.

The potential role of Human cytomegalovirus (hCM) infection in promoting neoplasia is an active area of scientific research. [1] Although still controversial, there is a growing body of evidence that links hCMV infection to a variety of malignancies, including those of the breast, prostate, colon, lung and brain (gliomas). [2-7] hCMV induces alterations in regulatory proteins and non-coding RNA...

In this paper we investigate and compare (evolutionary) patterns in the primary and secondary structure of four homologous E1a mRNAs of the adenovirus. Our main results are as follows: (1) The similarity of the coding regions of the mRNA sequences reflects both similarity in function (i.e., oncogenicity) and evolutionary divergence. (2) The similarity of the leader and the trailer regions refle...

DEPARTMENT OF PESTICIDE REGULATION MEDICAL TOXICOLOGY BRANCH SUMMARY OF TOXICOLOGY DATA Dimethomorph Chemical Code # 4003, Tolerance # 52068 SB 950 # New A.I. 6/01/01 I. DATA GAP STATUS Chronic toxicity, rat: No data gap, no adverse effect Chronic toxicity, dog: No data gap, no adverse effect Oncogenicity, rat: No data gap, possible adverse effect Oncogenicity, mouse: No data gap, no adverse ef...

Introduction of a left or right synthetic border repeat together with the overdrive sequence in an octopine Ti-plasmid deletion mutant, lacking the right border, resulted in the complete restoration of the oncogenicity of the mutant strain. However introduction of a border repeat without the overdrive, only restored oncogenicity partially. The overdrive sequence turned out to be able to stimula...