The observed incidence of ocular amyloid is to some extent a function of the diligence with which it is sought, recent reports having shown that it is by no means so rare as was once believed. In the last decade there have been several reports of conjunctival amyloidosis, associated in most instances with trachomatous pannus formation (Mathur and Mathur, 1959; Madangopal, I962; Richlin and Kuwa...

Amyloidosis is characterized by an abnormal extracellular deposition of amyloid in different organs, where it usually causes some type of dysfunction. Its cause is unknown. Five different types of amyloidosis have been described according to the underlying disease; immunoglobulin amyloidosis, familial amyloidosis, senile systemic amyloidosis, secondary amyloidosis and hemodialysis-associa...

BACKGROUND Heredo-oto-ophthalmo-encephalopathy (HOOE) is a dominantly inherited disease characterised by gradual loss of vision from the age of 20, progressive hearing loss from the late 20s, cerebellar ataxia in the 30s, and death in dementia in the fourth or fifth decade. Currently, no detailed description has been given of the ocular changes seen in HOOE. Therefore, the ocular changes of HOO...

amyloidosis is characterized by an abnormal extracellular deposition of amyloid in different organs, where it usually causes some type of dysfunction. its cause is unknown. five different types of amyloidosis have been described according to the underlying disease; immunoglobulin amyloidosis, familial amyloidosis, senile systemic amyloidosis, secondary amyloidosis and hemodialysis-associated am...

Several reviews of ocular amyloidosis have emphasized its origins in the conjunctiva and lid (Halasa, I965; Stansbury, I965; Smith and Zimmerman, I966). The occurrence of orbital amyloid has been considered extremely rare, its pathogenesis speculative, and its place in the spectrum of diseases associated with amyloid deposition uncertain (Groniowski, Bernardczykowa, and Norn, I965; Howard, I966...

BACKGROUND Conjunctival amyloidosis is a very rare condition, generally unilateral, and presents mostly as an isolated condition without systemic compromise. Our purpose is to present a new case of systemic amyloidosis with a bilateral conjunctival involvement. CASE PRESENTATION A 66-years-old caucasian female complaining of conjunctival hemorrhage and chemosis in both eyes for the last five ...

A 45-year-old man with primary systemic amyloidosis was found to have bilateral uveal effusions secondary to thickened sclera according to magnetic resonance imaging of the orbits. The patient was treated with bilateral sclerectomies and vortex vein decompression, and had an excellent outcome. Light microscopy of excised sclera revealed severe infiltration of the tissue by amyloid. To our knowl...

amyloidosis cutis dyschromica (acd) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. five other members of her family are also involved. biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorpho...