Mutations in two genes affect the formation of the boundary between midbrain and hindbrain (MHB): no isthmus (noi) and acerebellar (ace). noi mutant embryos lack the MHB constriction, the cerebellum and optic tectum, as well as the pronephric duct. Analysis of noi mutant embryos with neuron-specific antibodies shows that the MHB region and the dorsal and ventral midbrain are absent or abnormal,...

During the development of the zebrafish nervous system both noi, a zebrafish pax2 homolog, and ace, a zebrafish fgf8 homolog, are required for development of the midbrain and cerebellum. Here we describe a dominant mutation, aussicht (aus), in which the expression of noi and ace is upregulated. In aus mutant embryos, ace is upregulated at many sites in the embryo, while noi expression is only u...

Circulating angiogenic cells (CACs) are a diverse group that have been identified as predictors of cardiovascular health and are inversely proportional to cardiovascular disease (CVD) outcomes. Inactivity is a growing concern in industrialized nations and is an independent risk factor for CVD. There is limited evidence regarding the impact of reduced physical activity (rPA) on different CAC pop...

This paper is essentially a specification on analytical framework of a PhD thesis. The thesis itself is entitled: “Intellectual capital and economic performance of firms in the knowledge-based economy: a close look at evolution of modern enterprises” and is a study that seeks to understand the nature and function of the business firm as it is evolving with the changing today economy. The first ...

1569-190X/$ see front matter 2010 Elsevier B.V doi:10.1016/j.simpat.2010.05.002 * Tel./fax: +4021 4024886. E-mail addresses: [email protected], cr682003 The SOI transistors permanently offer new candidates as nanodevices. The nothing on insulator NOI transistor was recently derived from the nano SOI–MOSFET family. Their output characteristics were theoretical modelled with an exponential law,...

Abstract. This study tests the relationships between grandiose narcissism and affective, calculative, social-normative motivation to lead (MTL), avoidance lead, vulnerable affective MTL lead. Further, we assess moderating effect of narcissistic organizational identification (NOI). As expected, correlated positively with three dimensions MTL, though relationship disappeared when controlling for ...

This paper demonstrates how the Nation of Islam (NOI), a well known black nationalist organization, is utilizing notions of community to promote the activities and goals of its farm to other black people. The NOI ownsMuhammad Farms in rural southern Georgia, USA. Its stated purpose is to feed all black people in the United States. Historically, theNOI has occupied a radical space in the black c...

Io vedo le teorie scientifiche come costruzioni umane – reti progettate da noi per catturare il mondo.

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common polymorphism and enzymopathy in humans, affecting approximately 400 million people worldwide. It is responsible for various clinical manifestations, including favism, hemolytic anemia, chronic non-spherocytic hemolytic anemia, spontaneous abortion, and neonatal hyperbilirubinemia. Understanding the molecular mechanisms under...