Pulverized leaves samples of Newbouldia laevis were extracted by cold maceration using methanol. The extract was concentrated in vacuo to yield a reddish brown solid 120.191 g. crude methanol partitioned into n-hexane 0.1 g, dichloromethane 2.5 ethyl acetate 4.6 and 10.0 fractions via coarse chromatography. Methanol fraction gave the highest subjected further purification repeated column chroma...

A current trend in drug research is the desire to obtain novel antimicrobials with plant origins as an alternative therapy and a means curb antimicrobial resistance. This study evaluated phytochemistry antibacterial activity of ethyl acetate leaf extract Newbouldia laevis. The laevis was cold extracted Ethyl acetate. for it phytochemical constituents using standard methods effect against some c...

Underutilized species is referred to which little or no attention paid by the policymakers, agricultural researchers, and plant breeders. Medicinal plants used in traditional medicine have a natural origin, are effective, less expensive. Traditional doctors African countries make use of treating millions people. Albizia zygia, Alstonia boonei, Tetrapleura tetraptera, Newbouldia laevis Canarium ...

Based on traditional reports, the aqueous and ethanol extracts of the leaves of N. laevis were tested on isolated uterine preparations of non-pregnant rats. The effects of increasing cumulative concentrations of the extracts on the amplitude and frequency of spontaneously contracting uterine tissues were tested. Direct effects of the extracts and acetylcholine on uterine smooth muscle were also...