Aims and method Previous studies have shown variations in commissioning of neuropsychiatry services and this makes access to neuropsychiatric services a post-code lottery. In this survey, we approached all mental health and neuropsychiatric service commissioners within London to map current funding and commissioning arrangements, and explored perceived barriers to neuropsychiatric service commi...

Cannabinoid receptors (CBRs) are involved in neuropsychiatric disturbances including drug addiction. Studies show that single nucleotide polymorphisms (SNPs) of CNR1 and FAAH may contribute to drug addiction and other neuropsychiatric disorders. However, cannabinoid type-2 receptors (CB2Rs) in the CNS and their role in drug addiction and neuropsychiatric disorders have been much less well chara...

the neuropsychiatric manifestations of systemic lupus erythematosus are frequent. one of the most serious presentations is convulsion. this study was carried out to evaluate the relation between convulsion and anti-dna antibody levels. an analytic, retrospective case-controlled study was carried out, with reference to 1001 recorded cases of systemic sle lupus erythematosus in lupus unit, rheuma...

Neuropsychiatric symptoms, previously denominated as behavioural and psychological symptoms of dementia, are common features of Alzheimer's disease (AD) and are one of the major risk factors for institutionalization. At present, the role of the apolipoprotein E (APOE) gene in the development of neuropsychiatric symptoms in AD patients is unclear. In this paper, we summarized the findings of the...

Stroke is a leading cause of disability globally. Although neuropsychiatric symptoms are produced by stroke and adversely effect stroke outcome, it is unclear whether neuropsychiatric outcome can be improved by acute stroke treatment. The authors reviewed published acute ischemic stroke treatment trials to determine whether neuropsychiatric outcome measures were employed. Of the 190 trials revi...

OBJECTIVE To clarify the characteristics of neuropsychiatric symptoms in patients with idiopathic normal pressure hydrocephalus (iNPH). METHODS Neuropsychiatric symptoms of 64 iNPH patients with mild triad symptoms from three kinds of hospitals were evaluated with the Neuropsychiatric Inventory (NPI) and compared with 126 patients with Alzheimer's disease (AD). RESULTS The most frequently o...

OBJECTIVES To analyse frequency of HLA class II antigens (DR and DQ) and lymphocytotoxic autoantibodies in patients with systemic lupus erythematosus (SLE) and subsets with or without neuropsychiatric involvement. METHODS Ninety three patients with SLE (42 with neuropsychiatric features) were typed for HLA class II antigens and investigated for the presence of lymphocytotoxic autoantibodies b...