Precancerous lesions of oral mucosa, known as potentially malignant disorders in recent years, are consists a group diseases, which should be diagnosed the early stage. Oral leukoplakia, submucous fibrosis, and erythroplakia most common mucosal diseases that have very high transformation rate.

CONTEXT A validated discipline-specific questionnaire has been developed recently to assess the quality of life (QOL) in patients with chronic oral mucosal diseases. OBJECTIVE Use the Chronic Oral Mucosal Diseases Questionnaire for evaluating a diverse group of patients with chronic oral mucosal disease after therapy. DESIGN Prospective convenience sample. MAIN OUTCOME MEASURE Quality of ...

It is speculated more that 400 bacterial species reside in the ora1 eavity and the integrity of oral mucosa is maintained in such an environment. Oral mucosal cells such as epithelial cells and fibroblasts express a wide variety of receptors and preduce many immune regulators i, e., cytokines, chemokines, proteases, and chemical mediators and actively participate in host defenses by interacting...

It is speculated more that 400 bacterial species reside in the ora1 eavity and the integrity of oral mucosa is maintained in such an environment. Oral mucosal cells such as epithelial cells and fibroblasts express a wide variety of receptors and preduce many immune regulators i, e., cytokines, chemokines, proteases, and chemical mediators and actively participate in host defenses by interacting...

psoriasis and pemphigus vulgaris are two inflammatory and autoimmune diseases. their concomitant occurrence in one patient is very rare. we describe a 57-year-old patient with a history of severe plaque type psoriasis for 2 years. after a few months, he presented with disseminated bullae and mucosal erosions which were documented as pemphigus vulgaris. both of the diseases were successfully con...

Background and Objectives: The etiology, pathophysiology, nomenclature and clinical manifes-tation of solitary rectal ulcer syndrome (SRUS) is poorly understood. Aim: To examine the pathology of mucosal changes and clinical features of this syndrome. Materials and Methods: The mucosal biopsies of 19 pati...

In this review, the characteristics of gut microbiota changes in 11 metabolic diseases, as well research progress on their interventions, are summarized. The contributes to diseases through intestinal mucosal dysfunction, chronic inflammatory response, brain axis imbalance, gene regulation, insulin resistance, and action its metabolites. researches cause effect relationship mechanism relatively...