Regulatory On-Off Minimization (ROOM) is a model for predicting the behavior of metabolic networks in response to gene knockouts. It is based on minimizing the number of significant flux changes (hence, on/off) with respect to the wild-type. ROOM outperforms a previously suggested model, Minimization Of Metabolic Adjustment (MOMA), whose minimization metric is Euclidian. Furthermore, ROOM shows...

Multiple outcomes multivariate meta-analysis (MOMA) is gaining in popularity as a tool for jointly synthesizing evidence coming from studies that report effect estimates for multiple correlated outcomes. Models for MOMA are available for the case of the pairwise meta-analysis of two treatments for multiple outcomes. Network meta-analysis (NMA) can be used for handling studies that compare more ...

The role secretory IgM has in protecting splenic tissue from LPS-induced damage was assessed in mice incapable of secreting IgM but able to express surface IgM and IgD. Within seconds after LPS challenge, 99% of the (131)I-labeled LPS was found in the liver and the spleen of both sIgM-deficient and wild-type mice. In the spleen FITC-labeled LPS was found on the surface of 2F8(+) scavenger recep...

This paper deals with the problem of robust and perceptual logo watermarking for colour images. In particular, we investigate trade-off factors in designing efficient watermarking techniques to maximize the quality of watermarked images and the robustness of watermark. With the fixed size of a logo watermark, there is a conflict between these two objectives, thus a multiobjective optimization p...

In this paper, we present a cooperative odometry scheme based on the detection of mobile markers in line with the idea of cooperative positioning for multiple robots [1]. To this end, we introduce a simple optimization scheme that realizes visual mobile marker odometry via accurate fixed marker-based camera positioning and analyse the characteristics of errors inherent to the method compared to...

Mobile terminals like cellular phones and PDAs are a promising target platform for mobile advertising: The devices are widely spread, are able to present interactive multimedia content and offer as almost permanently carried along personal communication devices a high degree of reachability. But particular because of the latter feature it is important to pay great attention to privacy aspects a...

This article describes the strategies of North American government to help establish a Latin Collection in Museum Modern Art (MoMA) and role that Lincoln Kirstein had as collector works made up collection. The dialogue with various personalities culture tasks exhibition collection is analyzed. We emphasize how fine arts were spaces political weighting, areas usable by Good Neighbor politics. Fi...