نتایج جستجو برای: mice model

تعداد نتایج: 2422472  

Journal: :hepatitis monthly 0
xiumei li liver disease key lab, 458 hospital of pla, guangzhou, china guangze liu liver disease key lab, 458 hospital of pla, guangzhou, china meijuan chen liver disease key lab, 458 hospital of pla, guangzhou, china yang yang liver disease key lab, 458 hospital of pla, guangzhou, china yong xie liver disease key lab, 458 hospital of pla, guangzhou, china xiangping kong liver disease key lab, 458 hospital of pla, guangzhou, china; liver disease key lab, 458 hospital of pla, 801 dongfengdong road, 510600, guangzhou, guangdong, china. tel: +86-2087395343, fax: +86-2087371180

conclusions in conclusion, our observations indicated that pcdna3.1 (+)-hbv1.3c was superior to aav/hbv plasmid for establishment of persistent hbv infection by hi, in vivo, and this mouse model could be useful for studies of hepatitis virology and for the development of innovatory treatments for hbv infections. results in 60% of the mice injected with pcdna3.1 (+)-hbv1.3c, hbsag, hbeag, hbcag ...

Bei Qin, Hao He, Ke Chen Lei Zheng Li Hou, Ling Zhang Shaodan Tian, Tiantian Li, Xiaoyong Wu, Xinyi Chen, Yanping Sun, Zhixiong Chen

Objective(s): The main objective of this study was to investigate the variations of β-endorphin (β-EP), vasoactive intestinal peptide (VIP), serotonin (5-HT) and norepinephrine (NE) of immune thrombocytopenia (ITP) mice as well as the regulatory mechanism of prednison. Materials and Methods: Sixty BALB/c mice were randomly divided into control group, model group and prednison intervention grou...

Journal: :iranian journal of immunology 0
linge li department of otorhinolaryngology, the first affiliated hospital, xinjiang medical university, urumqi, xinjiang, china bin hu department of otorhinolaryngology, the first affiliated hospital, xinjiang medical university, urumqi, xinjiang, china juan feng department of otorhinolaryngology, the first affiliated hospital, xinjiang medical university, urumqi, xinjiang, china yu zhang department of otorhinolaryngology, the first affiliated hospital, xinjiang medical university, urumqi, xinjiang, china xi shou department of otorhinolaryngology, the first affiliated hospital, xinjiang medical university, urumqi, xinjiang, china yu tian department of otorhinolaryngology, the first affiliated hospital, xinjiang medical university, urumqi, xinjiang, china chunrong jiang

background:   h2-eb1 molecule which is the homolog of human hla-drb1 is proposed to be associated with allergic rhinitis (ar). construction of   h2-eb1 knockout animal models provides a tool to elucidate the role of h2-eb1 and ar pathogenesis. objective:   to establish the h2-eb1 knockout model and investigate the h2-eb1 functions in   h2-eb1 knockout mice as a model of ar. methods: the cre/lox...

Journal: :modares journal of medical sciences: pathobiology 2011
fariba khoshzaban fatemeh ghaffarifar abbas mahmmoudzadeh poornaki tooba ghazanfari mohsen naseri

objective: leishmaniasis is one of the six most common parasitic infections in tropical regions. there are different therapeutic modalities. however therapeutic resistance is developed and resulted in numerous problems. so evaluation of other therapeutic modalities is performed extensively. we compared the therapeutic response of cutaneous leishmaniasis with glucantime and garlic extract and it...

Journal: :journal of family and reproductive health 0
zohreh mazaheri cancer research center, cancer institute, tehran university of medical sciences, tehran, iran samad muhammadnejad reproductive health research center, tehran university of medical sciences, tehran, iran ahad muhammadnejad reproductive health research center, tehran university of medical sciences, tehran, iran moein zargarzadeh reproductive health research center, tehran university of medical sciences, tehran, iran maryam haghighi reproductive health research center, tehran university of medical sciences, tehran, iran mohammad ali oghabian research center for science and technology in medicine, tehran university of medical sciences, tehra

objective: to evaluate the potentiality of ovcar–3 cell line of ovarian adenocarcinoma as a xenograft model for ovarian adenocarcinoma in nude mice. materials and methods: the cell line isolated from advanced human ovarian adenocarcinoma, were inoculated to eight nude mice and two months later. established tumors were transferred to pathology laboratory to be prepared by h&e; staining and immun...

Bin Hu Chunrong Jiang Hua Zhang, Juan Feng Linge Li Xi Shou Yu Tian Yu Zhang

Background:   H2-EB1 molecule which is the homolog of Human HLA-DRB1 is proposed to be associated with allergic rhinitis (AR). Construction of   H2-Eb1 knockout animal models provides a tool to elucidate the role of H2-EB1 and AR pathogenesis. Objective:   To establish the H2-Eb1 knockout model and investigate the H2-EB1 functions in   H2-Eb1 knockout mice as a model of AR. Methods: The Cre/Lox...

Journal: :iranian journal of allergy, asthma and immunology 0
sule caglayan sozmen department of pediatrics, division of pediatric allergy and immunology, faculty of medicine,  dokuz eylul university, izmir,turkey meral karaman department of medical microbiology, faculty of medicine, dokuz eylul university, izmir, turkey serap cilaker micili department of histology and embryology, faculty of medicine, dokuz eylul university, izmir, turkey sakine isik department of pediatrics, division of pediatric allergy and immunology, faculty of medicine,  dokuz eylul university, izmir,turkey alper bagriyanik department of histology and embryology, izmir international biomedicine and genome institute (ibg-izmir), faculty of medicine, dokuz eylul university, izmir, turkey zeynep arikan ayyildiz department of pediatrics, division of pediatric allergy and immunology, faculty of medicine,  dokuz eylul university, izmir,turkey

quercetin is a dietary flavonoid which has anti-inflammatory effects. this study aimed to evaluate the influence of quercetin on histopathological aspects and airway epithelium in  allergic airway  inflammation mice model. twenty-eight balb/c mice were randomly divided into four groups: group i (control), group ii (untreated mice with allergic airway inflammation), group iii (allergic airway in...

Journal: :archives of medical laboratory sciences 0
ebrahim azimi professor; department of virology, tarbiat modares university, tehran, iran seyyede masoume athari faride afshari asie eftekhari seyyed shamsadin athari

background: black seed (bs) is used in traditional medicine as a therapy for a variety of diseases including allergic asthma. materials and methods: in the present study, anti-inflammatory and immunomodulatory effects of bs on cytokine gene expression, lung airway eosinophilia and goblet cell hyperplasia were examined in a mouse mice model of allergic asthma. groups of 6-week-old female balb/c ...

Journal: :modares journal of medical sciences: pathobiology 2014
rana sadafi mina jafarabadi mojdeh salehnia nasim ghorbanmehr

objective: endometriosis is a common disease in which the endometrial stroma and glands grow abnormally outside the uterine cavity. the establishment of animal models can be effective for determining the etiology of endometriosis. in this study we compare two endometriosis models using endometrial fragments and isolated cultured endometrial cells. methods: we obtained endometrial tissues that ...

Mahbub Mostofa, Md. Abdul Awal, Md. Abu bin Nyeem, Mohammad Ashraful Alam, Nusrat Islam, Sheikh Jamal Uddin,

The ethanol extract of the flowering top of Rosa damascena (Rosaceae) was assessed for neuropharmacological activities in mice using a number of experimental models. It significantly prolonged the pentobarbitone-induced sleeping time in mice, and showed mild to moderate central nervous system depressant activity when assessed by the hole cross and the open field tests in mice model when given...

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