نتایج جستجو برای: lymphatic irradiation
تعداد نتایج: 82795 فیلتر نتایج به سال:
Lymphatic metastasis is the major metastatic pattern of pancreatic cancer and considered as an independent risk factor of survival. However, there is still no effective way for the diagnosis and treatment for lymphatic metastases of pancreatic cancer. In this study, using albumin as a carrier of gemcitabine (Gem), further modified by pyropheophorbide-a, we have designed and synthesized a nanopa...
Lymphatic vessels play a crucial role in both the pathophysiology of tumors and in the spread cancer cells to lymph nodes. The effects of radiation on these vessels, however, are largely unknown. Here, we seek to describe the effects of ionizing radiation on normal and tumor-associated lymphatic vessels in vitro and in vivo. Clonogenic assays were employed to study the radiation dose response o...
Primary lymphangiomyomatosis is a benign tumour of lymphatic channels and lymph nodes, clinically manifested by chylous ascites. This disease is usually progressive and unresponsive to surgery, chemotherapy or irradiation. A case of a 36-year-old lady with chylous ascites due to underlying primary lymphangiomyomatosis is reported.
American cooperative group in 1972, the Intergroup Rhabdomyosarcoma Study Group has undertaken a series of clinical trials that have employed chemotherapy, surgery, and irradiation for local control. The addition of systemic chemotherapy has markedly improved long-term survival in affected children. These children now have an excellent prognosis with current multimodality therapy. A recent revi...
By ROBERT S. EVANS, M.D., AND ROSE T. DUANE, A.B. E VIDENCE is accumulating that transfused cells are destroyed at an accelerated rate in one type of acquired hemolytic anemia. ‘ Since normal cells as well as the patient’s are involved it is evident that a hemolysin is present which is active against all erythrocytes. In the few instances in which a hemolysin has been demonstrated in vitro it h...
Shortwave infrared (SWIR or NIR-II) light provides significant advantages for imaging biological structures due to reduced autofluorescence and photon scattering. Here, we report on the development of rare-earth nanoprobes that exhibit SWIR luminescence following X-ray irradiation. We demonstrate the ability of X-ray-induced SWIR luminescence (X-IR) to monitor biodistribution and map lymphatic ...
Whereas the role of the G-protein-coupled APJ receptor and its ligand, apelin, in angiogenesis has been well documented, the ability of the apelin/APJ system to induce lymphangiogenesis and lymphatic metastasis has been largely unexplored. To this end, we first show that APJ is expressed in lymphatic endothelial cells (LECs) and, moreover, that it responds to apelin by activating the apelinergi...
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