The aim of this study was to develop and apply an evaluation method for assessing the accuracy a novel 3D EPID back-projection algorithm in vivo dosimetry. Dosimetry Check (DC) 5.8 evaluated. A slab phantom homogeneously filled, or with air bone inserts, used fluence reconstruction different squared fields. VMAT plans anatomical sites were delivered on anthropomorphic phantom. Dose distribution...

Introduction: Contura is a balloon applicator that used to deliver intra cavity radiation for Partial Breast Irradiation (PBI) treatments. Contura with 4 peripheral lumens surrounding the central, for loading HDR sources from an after loader system can provide an asymmetric dose distribution and gives a more flexible shape of dose than earlier balloon applicators such as Mammo...

Verification of calculated lung dose in an anthropomorphic phantom is performed using two dosimetry media. Dosimetry is complicated by factors such as variations in density at slice interfaces and appropriate position on CT scanning slice to accommodate these factors. Dose in lung for a 6 MV and 10 MV anterior-posterior field was calculated with a collapsed cone convolution method using an ADAC...

Introduction: The present study was conducted with the aim of designing a liver phantom for dosimetry. To benchmark the results obtained by the developed liver phantom, another method was applied for the dosimetry of a real liver tissue using imaging. Materials and Methods: For the purpose of the study, a real liver tissue was converted into a phantom based on thegram-molecular weight of the co...

Benzo[a]pyrene (BaP) is a by-product of incomplete combustion of fossil fuels and plant/wood products, including tobacco. A physiologically based pharmacokinetic (PBPK) model for BaP for the rat was extended to simulate inhalation exposures to BaP in rats and humans including particle deposition and dissolution of absorbed BaP and renal elimination of 3-hydroxy benzo[a]pyrene (3-OH BaP) in huma...

BACKGROUND The optimal technique for performing lung IMRT remains poorly defined. We hypothesize that improved dose distributions associated with normal tissue-sparing IMRT can allow safe dose escalation resulting in decreased acute and late toxicity. METHODS We performed a retrospective analysis of 82 consecutive lung cancer patients treated with curative intent from 1/10 to 9/14. From 1/10 ...

Introduction: The Aeroform tissue expander device (ATED) is a novel alternative system for patients who have had mastectomy breast cancer (BC) and require adjuvant radiation therapy (RT), investigations are required when used during RT. We aim to compare RT dosimetry outcomes using volumetric modulated arc (VMAT) versus tangential intensity-modulated (t-IMRT) techniques planning post-mastectomy...

The lung dose contributed from thoron (Rn) and its progeny was usually neglected in the dose assessment because of the generally low concentrations. Recently, increased concentrations of Rn and its progeny were measured in the traditional residential dwellings in China, in dwellings in India and in other countries. The potential alpha energy concentration contributed from Rn and its decay produ...

objective: the bioscaffold can be used in tissue engineering and regenerative medicine. the scaffolds used in tissue engineering must have high porosity to facilitate accelerated angiogenesis for feeding cells and repelling cell waste outside the scaffold. in this experimental study, we attempted to produce lung three-dimensional scaffold and assay its effect on cell penetration and migration. ...

It is the purpose of this study to evaluate how self-expanding stents (SESs) affect esophageal cancer radiation planning target volumes (PTVs) and dose delivered to surrounding organs at risk (OARs). Ten patients were evaluated, for whom a SES was placed before radiation. A computed tomography (CT) scan obtained before stent placement was fused to the post-stent CT simulation scan. Three method...