نتایج جستجو برای: lassa fever

تعداد نتایج: 96729  

2014
Samuel Anu Olowookere Akinola Ayoola Fatiregun Olalere Omoyosola Gbolahan Ebenezer Gbenga Adepoju

BACKGROUND Lassa fever is highly contagious and commonly results in death. It is therefore necessary to diagnose and report any suspected case of Lassa fever to facilitate preventive strategies. This study assessed the preparedness of physicians in the diagnosis and reporting of Lassa fever. METHODS The study design was descriptive cross-sectional. The consenting medical doctors completed a s...

2012
Nadezhda E. Yun David H. Walker

Lassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100,000 patients annually in the endemic regions of West Africa with mortality rates for hospitalized patients varying between 5-10%. Currently, there are no approved vaccines against Lassa fever for use in humans. Here, we review the publishe...

2013
J Daniel Kelly M Bailor Barrie Rachel A Ross Brian A Temple Lina M Moses Daniel G Bausch

Poor quality housing is an infringement on the rights of all humans to a standard of living adequate for health. Among the many vulnerabilities of those without adequate shelter is the risk of disease spread by rodents and other pests. One such disease is Lassa fever, an acute and sometimes severe viral hemorrhagic illness endemic in West Africa. Lassa virus is maintained in the rodent Mastomys...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003
Walter H Haas Thomas Breuer Günter Pfaff Herbert Schmitz Päivi Köhler Marcel Asper Petra Emmerich Christian Drosten Uta Gölnitz Klaus Fleischer Stephan Günther

This study sought to assess the risk of secondary transmission after import of Lassa fever into Europe. A total of 232 persons exposed to a case of Lassa fever imported into Germany were identified. The level of exposure was determined for 157 persons (68%), and 149 (64%) were tested serologically. High-risk or close contact was reported by 30 (19%) of 157 persons. No symptomatic secondary infe...

2016
Tal Brosh-Nissimov

Lassa fever, a zoonotic viral infection, is endemic in West Africa. The disease causes annual wide spread morbidity and mortality in Africa, and can be imported by travelers. Possible importation of Lassa fever and the potential for the use of Lassa virus as an agent of bioterrorism mandate clinicians in Israel and other countries to be vigilant and familiar with the basic characteristics of th...

Journal: :Journal of vector borne diseases 2007
O Ogbu E Ajuluchukwu C J Uneke

Lassa fever is an acute viral zoonotic illness caused by Lassa virus, an arenavirus known to be responsible for a severe haemorrhagic fever characterised by fever, muscle aches, sore throat, nausea, vomiting and, chest and abdominal pain. The virus exhibits persistent, asymptomatic infection with profuse urinary virus excretion in the ubiquitous rodent vector, Mastomys natalensis. Lassa fever i...

2010
David Safronetz Job E. Lopez Nafomon Sogoba Sékou F. Traore’ Sandra J. Raffel Elizabeth R. Fischer Hideki Ebihara Luis Branco Robert F. Garry Tom G. Schwan Heinz Feldmann

To determine whether Lassa virus was circulating in southern Mali, we tested samples from small mammals from 3 villages, including Soromba, where in 2009 a British citizen probably contracted a lethal Lassa virus infection. We report the isolation and genetic characterization of Lassa virus from an area previously unknown for Lassa fever.

Journal: :Journal of clinical microbiology 1998
J Ter Meulen K Koulemou T Wittekindt K Windisch S Strigl S Conde H Schmitz

The nucleoprotein of Lassa virus, strain Josiah, was expressed in Escherichia coli as an N-terminally truncated, histidine-tagged recombinant protein. Following affinity purification the protein was completely denatured and spotted onto nitrocellulose membrane. A total of 1 microgram of protein was applied for detection of Lassa virus antibodies (LVA) in a simple immunoblot assay. Specific anti...

2016
Anna Grahn Andreas Bråve Martin Lagging Leif Dotevall David Ekqvist Helena Hammarström Helen Karlberg Nina Lagerqvist Martina Sansone Anders Tegnell Peter Ulleryd Marie Studahl

We describe an imported case of Lassa fever with both encephalopathy and bilateral sensorineural hearing deficit. Absence of fever during hospitalization, initially nonspecific symptoms, and onset of hearing deficit in a late stage of disease probably contributed to delayed diagnosis (14 days after admittance to hospital). The pathogenesis of neurological manifestations of Lassa fever is poorly...

2016
Joseph H.K. Bonney Edward O. Nyarko Sally-Ann Ohene Joseph Amankwa Ralph K. Ametepi Shirley C. Nimo-Paintsil Badu Sarkodie Prince Agbenohevi Michael Adjabeng Nicholas N.A. Kyei Samuel Bel-Nono William K. Ampofo

BACKGROUND Recent reports have shown an expansion of Lassa virus from the area where it was first isolated in Nigeria to other areas of West Africa. Two Ghanaian soldiers on a United Nations peacekeeping mission in Liberia were taken ill with viral haemorrhagic fever syndrome following the death of a sick colleague and were referred to a military hospital in Accra, Ghana, in May 2013. Blood sam...

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