Over the past few years, photogenic fabrication of metal oxide nanoparticles has attracted considerable attention, owing to simple, eco-friendly, and non-toxic procedure. Herein, we fabricated NiO altered their optical properties by doping with a rare earth element (lanthanum) using Sesbania grandiflora broth for antibacterial applications. The lanthanum was systematically studied. prepared nan...

BACKGROUND Lanthanum carbonate (FOSRENOL®) is an effective, well-tolerated phosphate binder. The ability of lanthanum to reduce serum phosphorus levels to ≤5.5 mg/dL in patients with end-stage renal disease (ESRD) was assessed in a clinical practice setting. METHODS A 16-week, phase IV study enrolled 2763 patients at 223 US sites to evaluate the efficacy of lanthanum carbonate in controlling ...

The g-aminobutyric acidA (GABA) receptor in the mammalian central nervous system is composed of pentameric combinations of a1–6, b1–4, g1–3, d1, and/or e1 subunit subtypes. Although each of the different subunits influences the functional properties of g-aminobutyric acidA receptors (GABARs), the a subunit subtypes have been shown to be important for activation of the receptor by GABA and pento...

A patient with end-stage renal disease (ESRD) on hemodialysis presented with fever, anorexia, and nausea shortly after starting oral lanthanum carbonate for phosphate control. Gastric and duodenal biopsies demonstrated diffuse histiocytosis with intracellular aggregates of basophilic foreign material. Transmission electron microscopy, an underutilized diagnostic test, revealed the nature of the...

The majority of patients with end-stage renal disease have hyperphosphataemia, which is associated with significant morbidity and mortality. Lanthanum carbonate has been introduced as a new treatment modality to lower serum phosphorus. But there has been ongoing concern about lanthanum accumulation in tissues, especially in liver. We describe the case of a woman with pre-existing liver disease,...

In this report intercellular material in developing cartilage and between reaggregating cartilage cells has been examined with lanthanum staining (3, 7, 13, 16) . The proteinpolysaccharides of cartilage have been extensively studied by biochemical methods (2, 8-10, 18-21), and proteinpolysaccharide extracted from cartilage has been shown to precipitate with lanthanum (2) . The lanthanum-stainin...

Precursors of lanthanum oxide and of (3La2O3, 5Ga2O3, SiO2) system were first elaborated then thermally decomposed into polycrystalline lanthanum oxide and langasite La3Ga5SiO14. The as prepared lanthanum oxide powder was then hydrated and carbonated to give hydroxicarbonates: thermal decomposition of these complex system La2O3-X(OH)y(CO3)z was studied by Fourier Transform infrared spectroscopy...

The effects of lanthanum on the resting membrane potential, action potential, membrane resistance, twitch tension, and potassium contracture were investigated and the localization of the drug was studied electron microscopically in isolated frog ventricular muscle. Lanthanum in concentration of 0.2 to 5 mM decreased the resting potential by about 5-8 mV, which was accompanied by an increase in ...

Escherichia coli heat-stable enterotoxin (ST) appears to cause intestinal fluid secretion by activating intestinal particulate guanylate cyclase. Recent studies suggest that chlorpromazine and quinacrine reduce the intestinal secretory response to ST and activation of guanylate cyclase by ST. We have examined the effects of lanthanum chloride, another agent that has been shown to inhibit calciu...

BACKGROUND Control of serum phosphate over the long term is essential in patients with end-stage renal disease. Six-month and 2-year extensions to a 6-month study evaluated the long-term safety, tolerability and efficacy of the new phosphate binder lanthanum carbonate. METHODS Patients who participated in a 6-month, randomized trial comparing lanthanum carbonate with calcium carbonate were el...