introduction: previous studies have shown that ghrelin inhibits the activity of hypothalamus –pituitary – thyroid (h–p-t) axis. it is also proved that ghrelin increases appetite via agouti related protein and neuropeptide y pathway, decreases t3 & t4 secretion and inhibits serotonin release from hypothalamic synaptosomes. serotonin may interact with ghrelin in control of thyroid hormones secret...

aflatoxins (afs) are natural contaminants of feed and feedstuffs, thus the study of the noxious effects ofthese agents on the male reproductive system is of outstanding importance. our aim for this study is theevaluation of the effects of oral administration of aflatoxin b1 on the reproductive hormonal changes in adult male rat. twenty eight wistar strain male rats were selected for this study....

Background: Spermatozoa are germ cells that have a pivotal role at fertilisation. Infertility is a problem with a large magnitude. Sperm damages are one of the factors that cause infertility. Reactive oxygen species (ROS) like hydrogen peroxide (H2O2), superoxide anion (O2−U) or molecules and/or hydroxyl radical (UOH) affect both male and female gametes. Cyclosporine A (CsA), a neutral lipophil...

AMELIORATIVE EFFECT OF SESAME OIL ON STREPTOZOTOCON- INDUCED OXIDATIVE STRESS IN MALE RAT HIPPOCAMPUS

Felbamate, 2-phenyl-1,3-propanediol dicarbamate, is a novel anticonvulsant that is effective against both chemically and electrically induced seizures in laboratory animals. Oncogenic studies were conducted in mice and rats to establish a preclinical safety profile for this drug. There was an increased incidence of hepatic cell adenoma in male and female mice and in female rats. There was an in...

1386. Toxicol Sci 60:291–292 (2001). 26. Narayanan L, Yu KY, Mattie DR, Fisher JW. Perchlorate induced thyroid hormonal changes in pregnant and lactating female rats, fetuses and nursing pups. Abstract 2069. Toxicol Sci 60:434 (2001). 27. Fisher J, Todd P, Mattie D, Godfrey D, Narayanan L, Yu K. Preliminary development of a physiological model for perchlorate in the adult male rat: a framework ...

This review paper examines the relationship between chemicals inducing excessive accumulation of alpha 2u-globulin (alpha 2u-g) (CIGA) in hyaline droplets in male rat kidneys and the subsequent development of nephrotoxicity and renal tubule neoplasia in the male rat. This dose-responsive hyaline droplet accumulation distinguishes CIGA carcinogens from classical renal carcinogens. CIGA carcinoge...

Aim: Long term persistently high blood glucose levels result in various complications and conditions diabetic patients. One of them is gastrointestinal disorders the other increased risk infectious diseases like parasitosis. The aim study to demonstrate intestinal parasites with techniques patients confirm frequency parasites.Methods: A total 65 type 2 Diabetes Mellitus were included study. Lab...

background: increase in world population is one of the serious and threatening issues in this century. therefore, it is vitally important to find safe and effective contraceptive methods, especially for men which already have few choices in this regard. medicinal plants that were used for contraception in ancient times could be good sources of investigation in this filed. ruta graveolens l. is ...