OBJECTIVE To determine the long-term outcomes of keratolimbal allograft (KLAL). METHODS Scores of such risks as infrequent blinking, blink-related microtrauma, conjunctival inflammation, elevated intraocular pressure, dry eye, symblepharon, lagophthalmos, and previous KLAL or penetrating keratoplasty (PKP) failure were calculated and recorded before, during, and after KLAL. Prolonged oral myc...

purpose: to investigate indications and methods of surgery in corneal transplantation in labbafinejad medical center from 2007 to 2009. methods: records of 1083 patients who had undergone corneal transplantation from 2007 to 2009 were reviewed. age, sex and indication and type of surgery were evaluated. results: patients included 709 (65.5%) male and 374 (34.5%) female subjects with mean age of...

OBJECTIVES To evaluate the clinical findings, treatment modalities and long-term prognosis of chemical and thermal burns of the cornea. MATERIALS AND METHODS Twenty-one patients (27 eyes) who were followed at two centers for corneal chemical and thermal burns between 2001 and 2013 were included. Eyes were grouped into four grades according to the severity of burn using Roper-Hall classificati...

PURPOSE The management of severe ocular surface disease due to limbal stem cell deficiency has changed dramatically. The concept of limbal stem cells, as the source of corneal epithelium revolutionised the therapeutic approach of ocular surface reconstruction. Deficiency of limbal stem cells results in blinding ocular surface diseases. Grafting viable limbal tissue, from either fellow healthy e...

purpose: to report the clinical findings and compare the outcomes of different surgical techniques evolved over time in a large series of patients with delayed-onset mustard gas keratitis (mgk). methods: this interventional retrospective case series includes patients with complications of delayed mgk. medical and surgical interventions to address dry eye, limbal ischemia and limbal stem cell de...

PURPOSE To determine the prevalence of keratopathy, cataract, and dry eye in a group of individuals with aniridia. METHODS We reviewed survey data from the Aniridia Foundation International (AFI) registry, which included 99 subjects who self-reported on corneal disease, cataract, and dry eye disease. RESULTS The average age of respondents was 25.3±18.6 years, with a range of 0 to 67. Of 99 ...

BACKGROUND/AIMS Limbal allotransplantation is increasingly being used for ocular surface repair in patients with limbal stem cell dysfunction. However, it is uncertain whether donor cells survive long term on the ocular surface and whether patients maintain the early benefits of the procedure. The aims of this study were to investigate the long term outcome of clinical limbal allografts and to ...

PURPOSE To describe the clinical presentation and management of late (>3.0 years) acute graft rejection in keratolimbal allograft (KLAL) recipients. METHODS This was a multicenter, retrospective observational case series. Six eyes of 6 patients with ocular surface transplant at a mean age of 36.2 years were seen at 3 tertiary referral centers for acute graft rejection between 2007 and 2013. M...