background: we investigated the efficacy of a mobile-based  bolus advisor app in comparison with the usual multiple daily  injections (mdis) in diabetic patients. materials and methods: in a nonrandomized, controlled clinical trial, 62 diabetic patients  were selected to receive a 12-week intensive glycemic control by either a mobile-based bolus advisor (app) or mdi in the usual manner.we compa...

conclusions the lh is a common problem in insulin-treated jordanian patients with t2dm. more efforts are needed to educate patients and health workers on simple interventions such as using shorter needles and frequent rotation of the insulin injection sites to avoid lh and improve glycemic control. results the overall prevalence of lh was 37.3% (27.4% grade 1, 9.7% grade 2, and 0.2% grade 3). t...

conclusions improvement of biomarkers of insulin sensitivity, including adiponectin and lipid metabolism, is an important therapeutic effect of medical nutrition therapy in obese patients with t2dm. objectives we evaluated the effects of calorie-restricted diet therapy on the circulating level of the serum lipid profile, glucose, insulin, and adiponectin in obese women with t2dm. materials and ...

conclusions this case highlights the fact that fhr and ghd may coexist, with possible masking effect of one on the other, thereby misleading the approach, posing large impacts on therapy, which has historically been a difficult challenge in fhr patients. introduction coincided familial hypophosphatemic rickets (fhr) and hypopituitarism is a rare condition. growth hormone deficiency (ghd) evalua...

Background: Magnesium deficiency plays a key role in obesity and decreases insulin sensitivity. In our previous study, significant evidence was provided for the contribution of oral Mg supplement that could improve insulin sensitivity and body weight in animal trials. The purpose of the present study was to investigate the effects of an herbal supplement containing 300 mg magnesium sulfate on l...

AimsWe aimed to review insulin dosing recommendations, regulation and its determinants, glycaemic response carbohydrates, the efficacy safety of therapy in different races/ethnicities.MethodsWe searched for articles PubMed Google Scholar databases up 31 March 2021, with following keywords: “ethnicity”, “diabetes”, “insulin”, “history insulin”, “insulin therapy”, “food/rice”, “carbohydrate intak...

The quality of life children with type I diabetes and lifestyle depend lamentably on the level glucose, frequency, mode administration insulin, peculiarities diet. To a large extent, methods subcutaneous injection, but also insulin by pump are determined therapy, dose administered, body’s response, motor skills, etc.

Insulin therapy has been the best choice for the clinical management of diabetes mellitus. The current insulin therapy is via subcutaneous injection, which often fails to mimic the glucose homeostasis that occurs in normal individuals. Oral delivery is the most convenient administration route. However, insulin cannot be well absorbed orally because of its rapid enzymatic degradation in the gast...