background and objectives: staphylococcus aureus is an important cause of nosocomial and community-acquired infections in every region of the world. clindamycin is one of the alternative agents used to treat s. aureus infections and accurate identification of clindamycin resistance is important to prevent therapeutic failure. unfortunately, inducible clindamycin resistance is not detected by st...

background and objectives: accurate designation of antimicrobial susceptibility pattern of the infecting microorganisms is an important crucial factor in making appropriate therapeutic decisions. macrolide, lincosamide and streptogramin b antibiotics are in a family, reserved as an alternative approach in treatment of resistant gram positive cocci. amongst them, clindamycin has been considered ...

background staphylococcus aureus is a common pathogen in hospitals and communities. antibiotic resistance is a major public health problem. objectives the aim of this study was the determination of antimicrobial susceptibility patterns and to perform molecular detection of macrolide and lincosamide-resistance genes in clinical s. aureus isolates from kerman, iran. conclusions a high prevalence ...

background: macrolides, lincosamides and type b streptogramins (mlsb) are commonly used for the treatment of staphylococcal infections. inducible mlsb resistance (imlsb) cannot be identified by standard methods of antibiotic susceptibility testing. d-test appears to be a reliable indicator of imlsb strains. the aim of this study was to determine the prevalence of clindamycin resistance phenotyp...

conclusions in our study, inducible clindamycin resistance rate was 4%; so it is necessary to conduct d-test regularly by disc diffusion for this bacterium. resistance to erythromycin, clindamycin, ciprofloxacin and gentamicin was significantly higher in mrsa isolates than methicillin susceptible staphylococcus aureus (mssa), although the methicillin resistance prevalence was low. background st...

background: streptococcus group b (gbs) or streptococcus agalactiae is typically associated with neonatal disease and infection in pregnant women. mortality of gbs sepsis in neonates is over 50% and is particularly high in preterm infants. gbs also causes invasive infection in pregnant and non-pregnant women including urinary tract infection (uti). penicillin-derived antibiotics remained as cho...

background: clindamycin inducible resistant staphylococcus aureus (s.aureus) isolates can cause failure in treatment with this antibiotic. biofilm production via polysaccharide intercellular adhesion (pia) contributes in the colonization of s. aureus, resulting in the initiation of different diseases. the aim of this study was to detect icaadbc genes among isolates of s.aureus with inducible re...

background and objectives: resistance to macrolide can be mediated by erm and msra genes in staphylococcus aureus . there are the evidences that show erm genes may be causative agent of inducible or constitutive resistance. the aim of this study was to investigate the incidence of inducible clindamycin resistance and determine the most frequency of erm and msr a genes among s. aureus isolates. ...

Background and Objectives: Staphylococcus aureus is an important cause of nosocomial and community-acquired infections in every region of the world. Clindamycin is one of the alternative agents used to treat S. aureus infections and accurate identification of clindamycin resistance is important to prevent therapeutic failure. Unfortunately, inducible clindamycin resistance is ...