This paper looks for any correlation between the internal dynamics of elliptical galaxies and the relatively mild nuclear activity found in many such systems. We show that there is such a relation in the sense that the active ellipticals tend to be significantly less rotationally supported than their inactive cousins. The correlation can partly be related to the galaxies’ luminosities: the brig...

Protein actions are usually discussed in terms of static structures, but function requires motion. We find a strong correlation between phosphorylation-driven activation of the signaling protein NtrC and microsecond time-scale backbone dynamics. Using nuclear magnetic resonance relaxation, we characterized the motions of NtrC in three functional states: unphosphorylated (inactive), phosphorylat...

We propose a statistical model of large random network with high connectivity in order to describe the behavior E. coli cells after exposure acute stress. The building blocks this are feedback cycles typical genetic and metabolic networks cell. Each node on is spin degree freedom representing component cell's that can be one two states: active or inactive. interconnected by regulation exchange ...

We consider the dynamics of a disordered p -spin model with p=2 , analyzing the dynamics within Ruelle's thermodynamic formalism, We use an indicator of the dynamical activity to construct the relevant dynamical Gibbs ensemble. We prove that the dynamics in the low-temperature (spin-glass) phase of the model take place at a second-order phase transition between dynamically active and inactive t...

Cytoplasmic Polyadenylation Element Binding protein (CPEB) is an RNA binding protein involved in dendritic delivery of mRNA and activity-dependent, polyadenylation-induced translation of mRNAs in the dendritic arbor. CPEB affects learning and memory and impacts neuronal morphological and synaptic plasticity. In neurons, CPEB is concentrated in ribonucleoprotein (RNP) granules that distribute th...

Receiver domains are key molecular switches in bacterial signaling. Structural studies have shown that the receiver domain of the nitrogen regulatory protein C (NtrC) exists in a conformational equilibrium encompassing both inactive and active states, with phosphorylation of Asp54 allosterically shifting the equilibrium towards the active state. To analyze dynamical fluctuations and correlation...