نتایج جستجو برای: humoral immune responses

تعداد نتایج: 609396  

Introduction: The importance of genetically modified microorganisms, including probiotics, now widely have considered as attractive vehicles for mucosal delivery of therapeutic molecules. Previous studies have indicated that mucosal administration of these molecules can effectively trigger humoral along with cellular immune responses. Therefore, development of induction of mucosal immune respon...

Increased susceptibility of birds to avian pathogens in intensive husbandry system has emphasized on necessity of improvement of innate and specific immune responses of birds by the fast establishment of a beneficial microflora and immune stimulator factors to guarantee healthy and low-price products. During this study, 192 one-day-old broiler chicks (Ross-380) in four groups with three replica...

Background and purpose: Toxoplasma gondii (T. gondii) as a causative agent of toxoplasmosis, is an obligate intracellular parasite which is excreted by the cat's feces. Efforts have been made for the development of toxoplasmosis vaccine, but none led to developing a vaccine with protective immune response to the parasite. Adjuvants are essential for vaccine formulation to create strong immune r...

Journal: :vaccine research 0
r vahabpour pasteur institute of iran mr aghasadeghi pasteur institute of iran f goudarzifar pasteur institute of iran h keyvani pasteur institute of iran a ataei- pirkooh pasteur institute of iran sh monavari pasteur institute of iran

introduction: glycoprotein b (gb) is the major antigen for induction of humoral responses against human cytomegalovirus (hcmv) making it an attractive candidate for immune prophylaxis. in the present study, the humoral immune response of balb/c mice to a truncated hcmv gb protein fused with gfp was evaluated. methods: the truncated gb coding sequence was synthesized and cloned in pegfpn1 eukary...

Journal: :hepatitis monthly 0
christine hartoonian department of pharmaceutical biotechnology and biotechnology research center, faculty of pharmacy, tehran university of medical sciences, tehran, ir iran; department of virology, pasteur institute of iran, tehran, ir iran zargham sepehrizadeh department of pharmaceutical biotechnology and biotechnology research center, faculty of pharmacy, tehran university of medical sciences, tehran, ir iran; department of pharmaceutical biotechnology and biotechnology research center, faculty of pharmacy, tehran university of medical sciences, tehran, ir iran. tel: +98-2164122301, fax: + 98-2166461178, e-mail: kayhan azadmanesh, department of virology, pasteur institute of iran, tehran, ir iran. tel/fax: +98-2166496682 mojtaba tabatabai yazdi department of pharmaceutical biotechnology and biotechnology research center, faculty of pharmacy, tehran university of medical sciences, tehran, ir iran yong suk jang departments of molecular biology and bioactive material sciences, institute for molecular biology and genetics, chonbuk national university, jeonju, korea lida langroudi department of virology, pasteur institute of iran, tehran, ir iran parisa amir kalvanagh department of virology, pasteur institute of iran, tehran, ir iran; department of immunology, faculty of medical sciences, tarbiat modaress university, tehran, ir iran

conclusions these results exhibited the immuno potentiator effects of mip-3beta plasmid when coadministrated with the hcv core dna vaccine. complimentary studies integrating mip-3beta as a genetic adjuvant in hcv-core-dna vaccination models are warranted. results mice covaccinated with mip-3beta elicited an enhanced th1 biased systemic immune response as evidenced by higher ifn-γ/il-4 and anti-...

Journal: :veterinary research forum 2015
alireza talebi amir amani masoud pourmahmod poya saghaei reza rezaie

increased susceptibility of birds to avian pathogens in intensive husbandry system has emphasized on necessity of improvement of innate and specific immune responses of birds by the fast establishment of a beneficial microflora and immune stimulator factors to guarantee healthy and low-price products. during this study, 192 one-day-old broiler chicks (ross-380) in four groups with three replica...

Hepatitis C virus (HCV) is responsible for a vast majority of liver failure cases. HCV is a kind of blood disease appraised to chronically infect 3% of the worlds’ population causing significant morbidity and mortality. Therefore, a complete knowledge of humoral responses against HCV, resulting antibodies, and virus-receptor and virus-antibody interactions, are essential to design a vaccine. HC...

Journal: :modares journal of medical sciences: pathobiology 2007
fatemeh roudbari farzaneh sabahi mohammad nabi sarbolouki farzaneh barkhordari mehdi mahdavi

objective: the global hiv epidemic continues to expand and exceeding previous predictions. an effective vaccine represents the best hope to curtail the hiv epidemic. dna vaccines induce humoral and cellular responses and mimic live vaccines without their pathogenic potential. the importance of cd8+ ctl responses in controlling hiv and siv viremia has led to production of a series of vaccine can...

Journal: :modares journal of medical sciences: pathobiology 2005
ali reza nakhaee sima rafati ali-hatef salmanian mohammad taghikhani mehdi mohebali

purpose: evaluation of humoral and cellular immune responses of naturally infected dogs against type i (rcpb) (recombinant cycsteine proteinase b), and ii (rcpa) (recombinant cycsteine proteinase a) recombinant cysteine proteinases and c-terminal extension (cte) of leishmania infantum (l. infantum). materials and methods: in this study, fourteen infected dogs (7 with symptoms, 7 asymptomatics)...

Journal: :iranian journal of parasitology 0
a nikpay s nabian s rahbari p shayan n alidadi

background : ticks are blood feeder acarians that feed on variety of animals and introduce a wide variety of molecules to their host immune system and some of them may stimulate host immune system to produce antibodies. this study was carried out to detect humoral immune responses following boophilus annulatus infestation. methods: seven cattle were each experimentally infested with 10000 b. an...

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