OBJECTIVE Type 2 diabetes (T2D) and its complications form a global healthcare burden but the exact impact in some geographical regions is still not well documented. We describe the healthcare resource usage (HRU) associated with T2D in Africa, the Middle East, South Asia, Eurasia and Turkey. RESEARCH DESIGN AND METHODS In the fifth wave of the International Diabetes Management Practices Stud...

Background Bone metastases and lytic lesions due to multiple myeloma are common in advanced cancer and can lead to debilitating complications (skeletal-related events [SREs]), including requirement for radiation to bone. Despite the high frequency of radiation to bone in patients with metastatic bone disease, our knowledge of associated healthcare resource utilization (HRU) is limited. Method...

The access matrix model as formalized by Harrison, Ruzzo, and Ullman (HRU) has broad expressive power. Unfortunately, HRU has weak safety properties (i.e., the determination of whether or not a given subject can ever acquire access to a given object). Most security policies of practical interest fall into the undecidable cases of HRU. This is true even for monotonic policies (i.e., where access...

This study aimed to increase the understanding of health resource utilization (HRU) associated with skeletal-related events (SREs) occurring in patients with bone metastases secondary to advanced prostate cancer. A total of 120 patients from Germany, Italy, Spain and the United Kingdom were enrolled in this observational study. They had bone metastases secondary to prostate cancer and had exper...

In January of 2013, I took the helm from my colleague, Professor John Collins, to steer the ship that is Human Reproduction Update (HRU), a review journal owned by the European Society of Human Reproduction and Embryology (ESHRE). It’s with great pleasure that I reflect on the transition during the first 3 years of my editorship. HRU was first published in 1995 by Sir Robert Edwards: it has sin...

Health care resource consumption is a growing concern. The aim of this study was to examine the associations between diet quality and body mass index with health care resource use (HRU) in a cohort of advanced age. Participants in the Geisinger Rural Aging Study (n=5,993) were mailed demographic and dietary questionnaires in 2009. Of those eligible, 2,995 (50%; 1,267 male, 1,728 female; mean ag...

In this paper we show that the Schematic Protection Model (SPM) subsumes several well-known protection models as particular instances. We show this for a diverse collection of models including the Bell-LaPadula multi-level security model, take-grant models, and grammatical protection systems. Remarkably SPM subsumes these models within its known e ciently decidable cases for safety analysis (i....

OBJECTIVES Irritable bowel syndrome (IBS) affects nearly one in seven Americans. Significant national variations in care may exist, due to a current lack of standardized diagnosis and treatment algorithms; this can translate into a substantial additional economic burden. The study examines healthcare resource utilization in patients with IBS and in the subset of IBS patients with constipation (...

The Soil and Water Assessment Tool SWAT was implemented in Northwest Arkansas to investigate flow and sediment predictive ability at multiple subbasin and hydrologic response units HRU distributions. The objectives of this study were to use SWAT and identify differences in annual predicted flow and sediment response of a watershed considering two subbasin delineations with six different HRU dis...

INTRODUCTION The present study aimed to assess disease control, health resource utilization (HRU), and healthcare costs, and their predictors in gout patients across the USA, UK, Germany, and France. METHODS Data were extracted from the PharMetrics Plus (USA), Clinical Practice Research Datalink-Hospital Episode Statistics (UK), and Disease Analyzer databases (Germany and France) for adult go...