OBJECTIVE The aim of this study is to evaluate the clinical and prognostic values of persistence of anti-hepatitis B core immunoglobulin M antibody in asymptomatic adults chronic hepatitis B surface antigen anti-hepatitis Be carriers and its absence in others. METHODS Fifty-two hepatitis B surface antigen/anti-hepatitis Be carriers with and 32 without anti-hepatitis B core immunoglobulin M ma...

Repeated administration of an intravenous immunoglobulin containing antibody to hepatitis B e antigen (anti-HBe) and antibody to hepatitis B core antigen (anti-HBc) but free of antibody to hepatitis B surface antigen (anti-HBs) before and after the inoculation of 10(4.9) 50% chimpanzee infective doses of hepatitis B virus (HBV) markedly prolonged the incubation period of HBV in experimentally i...

Without intervention, a pregnant woman who is a chronic hepatitis B carrier is at risk of transmitting hepatitis B and of her infant becoming a chronic carrier and having a significantly increased lifetime risk of developing liver cancer or cirrhosis. Hepatitis B vaccine and immunoglobulin reduce the risk of the baby becoming a carrier, but with only a short window period after birth to deliver...

OBJECTIVES Living-donor kidney transplant from donors who are chronically infected with hepatitis B virus can be considered as a possibility to compensate for insufficiency of organ transplants, particularly in a hepatitis B virus endemic country. In this study, the safety and efficacy were reviewed retrospectively in living-donor kidney transplant from donors who were chronically infected with...

A collection of 104-fecal specimens from 45 patients with hepatitis A, 14 patients with hepatitis B, 10 patients with non-A, non-B hepatitis, 6 patients with diseases other than hepatitis, and 18 healthy adults were studied for the presence of secretory immunoglobulin A and immunoglobulin M to hepatitis A virus by solid-phase enzyme-linked immunosorbent assay and immune electron microsopy. Spec...

conclusions one in five patients undergoing maintenance dialysis in hamadan is seropositive for hepatitis e immunoglobulin g antibody. future studies are needed to investigate the factors contributing to the observed high prevalence rate and the possibility of parenteral transmission of hepatitis e. results thirty patients (19.2%), were seropositive. seropositive patients were not significantly...

Hepatitis B immunoglobulin (HBIG) is an effective treatment for hepatitis B, including postexposure prophylaxis of HBV infection, prevention reinfection in liver transplant patients, and reducing sexual transmission. This study investigated the synthesis human IgG antibodies that specifically target HBsAg subtype adr CHL-YN cells, a newly established cell line grows faster than CHO-K1. To achie...

Perinatal transmission of hepatitis B virus is the infection of infants at birth by mothers who are positive for hepatitis B surface antigen. Around 85% of babies born to mothers who are also positive for hepatitis B e antigen become infected. Immunoprophylaxis initiated shortly after birth— that is, after exposure to the virus—can prevent perinatal transmission. Passive prophylaxis with hepati...

PURPOSE In spite of the success of hepatitis B immunization, still a significant proportion of childhood hepatocellular carcinoma (HCC) failed to be prevented by the hepatitis B immunization program. This study is aimed to investigate the problems in the HCC prevention in children. EXPERIMENTAL DESIGN All HCC children ages 6 to 14 diagnosed between 1981 and 2000 in Taiwan were collected from ...