The present study examines the association between General Factor of Personality (GFP) and working memory its etiology with a behavioral genetic approach. GFP, which explains common variance among lower-order personality traits, is considered to reflect social effectiveness. Meanwhile, also plays significant role in competence. Hence, we expected substantial GFP memory. A total 253 Japanese twi...

Abstract Introduction There remains a paucity of novel therapeutics for limb salvage in patients with critical ischemia (CLI) whom revascularization procedures have failed and amputation is imminent. We shown that E-selectin+/Mesenchymal Stem Cell (MSC) injections into the ischemic tissue CLI mouse model improves function. Thus, we sought to determine mechanism action E-selectin+/MSC’s pro-angi...

Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...

Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...

Superinfection exclusion (SIE) is an antagonistic interaction between identical or closely related viruses in host cells. Previous studies by us and others led to the hypothesis that SIE was elicited one more proteins encoded genomes of primary viruses. Here, we tested this using Turnip mosaic virus (TuMV), a member genus Potyvirus family Potyviridae, with significant economic consequences. To ...

ABSTRACT Mislocalization of the TAR DNA-binding protein 43 (TDP-43; encoded by TARDBP) from nucleus to cytoplasm is a common feature neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). The downstream in vivo cellular effects this mislocalization are not well understood. To investigate impact mislocalized TDP-43 on neuronal cell ...

CRISPR/Cas9 system is a powerful gene editing tool in vivo and in vitro. Currently, CRISPR/Cas9 delivery cells or tissue with different vehicles are available, and Adeno- associated virus (AAV) in one of them. Due to AAV packaging size limitation, AAV base vectors that carry CRISPR/Cas9 system do not have florescent tag like GFP for simple detection and navigation of cells, containing AAV. The ...

Transient expression of proteins in plants has become a choice to facilitate recombinant protein production with its fast and easy application. On the other hand, host defensive mechanisms have been reported to reduce the efficiency of transient expression in plants. Hence, this study was designed to evaluate the effect of cap analog and Potato virus A helper component proteinase (PVA HC-Pro) o...