نتایج جستجو برای: focal segmental glomerulosclerosis

تعداد نتایج: 79697  

2010
Glen S. Markowitz Samih H. Nasr Vivette D. D’Agati

Background and objectives: Treatment with IFN is rarely associated with nephrotic syndrome and renal biopsy findings of minimal-change disease or FSGS. Design, setting, participants, & measurements: We report 11 cases of collapsing FSGS that developed during treatment with IFN and improved after discontinuation of therapy. Results: The cohort consists of seven women and four men with a mean age...

Journal: :The New England journal of medicine 2011
Caterina Mele Paraskevas Iatropoulos Roberta Donadelli Andrea Calabria Ramona Maranta Paola Cassis Simona Buelli Susanna Tomasoni Rossella Piras Mira Krendel Serena Bettoni Marina Morigi Massimo Delledonne Carmine Pecoraro Isabella Abbate Maria Rosaria Capobianchi Friedhelm Hildebrandt Edgar Otto Franz Schaefer Fabio Macciardi Fatih Ozaltin Sevinc Emre Tulin Ibsirlioglu Ariela Benigni Giuseppe Remuzzi Marina Noris

BACKGROUND Focal segmental glomerulosclerosis is a kidney disease that is manifested as the nephrotic syndrome. It is often resistant to glucocorticoid therapy and progresses to end-stage renal disease in 50 to 70% of patients. Genetic studies have shown that familial focal segmental glomerulosclerosis is a disease of the podocytes, which are major components of the glomerular filtration barrie...

2014
Dorothee Heck Miriam Mergen Athina Ganner Jaroslav Pelisek Irina Mader Cornelius Weiller Wolf-Dirk Niesen

BACKGROUND Polyneuropathy organomegaly endocrinopathy M-protein skin changes (POEMS) syndrome is a rare cause of polyneuropathy. Calciphylaxis, a severe disease leading to necrotic ulcers of the skin, is associated with POEMS syndrome and also with renal disease. This case report describes a patient with POEMS syndrome plus primary focal segmental glomerulosclerosis. CASE PRESENTATION A 27-ye...

2017
Vivekanand Jha Johan van der Vlag

Focal segmental glomerulosclerosis (FSGS) represents the most common primary glomerular disease responsible for the development of end-stage renal disease (ESRD) in the United States (US). The disease progresses from podocyte injury to chronic kidney disease (CKD), ultimately leading to total nephron degeneration. Extensive basic science research has been conducted to unwind the mechanisms of F...

2017
Vasil Peev Eunsil Hahm Jochen Reiser

Focal segmental glomerulosclerosis (FSGS) represents the most common primary glomerular disease responsible for the development of end-stage renal disease (ESRD) in the United States (US). The disease progresses from podocyte injury to chronic kidney disease (CKD), ultimately leading to total nephron degeneration. Extensive basic science research has been conducted to unwind the mechanisms of F...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003
Alexander J Howie

Minimal change nephropathy is relatively uncontroversial. This can be defined as the condition associated with the nephrotic syndrome in which glomeruli have no abnormality on light microscopy. Segmental sclerosing glomerular disorders are often called focal segmental glomerulosclerosis, one of the most controversial terms in kidney disease. The tubular opening is the earliest site at which seg...

Journal: :Nephrology Dialysis Transplantation 1999

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